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Spectral-based subspace clustering methods have proved successful in many challenging applications such as gene sequencing, image recognition, and motion segmentation. In this work, we first propose a novel spectral-based subspace…

Machine Learning · Statistics 2021-06-09 Hankui Peng , Nicos G. Pavlidis

Although there is no shortage of clustering algorithms proposed in the literature, the question of the most relevant strategy for clustering compositional data (i.e., data made up of profiles, whose rows belong to the simplex) remains…

Statistics Theory · Mathematics 2018-05-17 Antoine Godichon-Baggioni , Cathy Maugis-Rabusseau , Andrea Rau

DNA sequence classification is a fundamental task in computational biology with vast implications for applications such as disease prevention and drug design. Therefore, fast high-quality sequence classifiers are significantly important.…

Machine Learning · Computer Science 2023-11-07 Marcel Khalifa , Barak Hoffer , Orian Leitersdorf , Robert Hanhan , Ben Perach , Leonid Yavits , Shahar Kvatinsky

High-dimensional omics datasets are routinely visualized as heatmaps, where color intensities reveal co-expression patterns and correlations. However, modern omics technologies increasingly generate matrices so large that existing visual…

Genomics · Quantitative Biology 2026-04-21 Osho Rawal , Rex Lu , Edgar Gonzalez-Kozlova , Sacha Gnjatic , Zeynep H. Gümüş

Deep learning models have become widely adopted in various domains, but their performance heavily relies on a vast amount of data. Datasets often contain a large number of irrelevant or redundant samples, which can lead to computational…

Audio and Speech Processing · Electrical Eng. & Systems 2023-09-22 Boris Bergsma , Marta Brzezinska , Oleg V. Yazyev , Milos Cernak

There is a growing need for unbiased clustering methods, ideally automated. We have developed a topology-based analysis tool called Two-Tier Mapper (TTMap) to detect subgroups in global gene expression datasets and identify their…

Genomics · Quantitative Biology 2018-01-08 Rachel Jeitziner , Mathieu Carrière , Jacques Rougemont , Steve Oudot , Kathryn Hess , Cathrin Brisken

We present a novel coupled two-way clustering approach to gene microarray data analysis. The main idea is to identify subsets of the genes and samples, such that when one of these is used to cluster the other, stable and significant…

Biological Physics · Physics 2009-11-06 G. Getz , E. Levine , E. Domany

Co-clustering simultaneously clusters rows and columns, revealing more fine-grained groups. However, existing co-clustering methods suffer from poor scalability and cannot handle large-scale data. This paper presents a novel and scalable…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-03-20 Zihan Wu , Zhaoke Huang , Hong Yan

It is more and more common to explore the genome at diverse levels and not only at a single omic level. Through integrative statistical methods, omics data have the power to reveal new biological processes, potential biomarkers, and…

Methodology · Statistics 2021-03-05 Morgane Pierre-Jean , Florence Mauger , Jean-François Deleuze , Edith Le Floch

In this paper, we develop a method for unsupervised clustering of two-way (matrix) data by combining two recent innovations from different fields: the Sparse Subspace Clustering (SSC) algorithm [10], which groups points coming from a union…

Machine Learning · Computer Science 2015-02-24 Eric Kernfeld , Shuchin Aeron , Misha Kilmer

Subtype Discovery consists in finding interpretable and consistent sub-parts of a dataset, which are also relevant to a certain supervised task. From a mathematical point of view, this can be defined as a clustering task driven by…

Machine Learning · Statistics 2021-07-06 Robin Louiset , Pietro Gori , Benoit Dufumier , Josselin Houenou , Antoine Grigis , Edouard Duchesnay

Subspace clustering algorithms are used for understanding the cluster structure that explains the dataset well. These methods are extensively used for data-exploration tasks in various areas of Natural Sciences. However, most of these…

Machine Learning · Computer Science 2022-11-15 Ashutosh Singh , Ashish Singh , Aria Masoomi , Tales Imbiriba , Erik Learned-Miller , Deniz Erdogmus

Estimating the number of clusters (K) is a critical and often difficult task in cluster analysis. Many methods have been proposed to estimate K, including some top performers using resampling approach. When performing cluster analysis in…

Methodology · Statistics 2019-09-05 Yujia Li , Xiangrui Zeng , Chien-Wei Lin , George Tseng

In many real-world problems, we are dealing with collections of high-dimensional data, such as images, videos, text and web documents, DNA microarray data, and more. Often, high-dimensional data lie close to low-dimensional structures…

Computer Vision and Pattern Recognition · Computer Science 2013-02-06 Ehsan Elhamifar , Rene Vidal

In this thesis, we propose several modelling strategies to tackle evolving data in different contexts. In the framework of static clustering, we start by introducing a soft kernel spectral clustering (SKSC) algorithm, which can better deal…

Social and Information Networks · Computer Science 2014-11-24 Rocco Langone

Subspace clustering has become widely adopted for the unsupervised analysis of hyperspectral images (HSIs). Recent model-aware deep subspace clustering methods often use a two-stage framework, involving the calculation of a…

Computer Vision and Pattern Recognition · Computer Science 2025-06-16 Xianlu Li , Nicolas Nadisic , Shaoguang Huang , Nikos Deligiannis , Aleksandra Pižurica

Evolutionary computation (EC) algorithms, such as discrete and multi-objective versions of particle swarm optimization (PSO), have been applied to solve the Feature selection (FS) problem, tackling the combinatorial explosion of search…

Neural and Evolutionary Computing · Computer Science 2019-01-28 Hassen Dhrif , Luis G. Sanchez Giraldo , Miroslav Kubat , Stefan Wuchty

Subspace clustering aims to find groups of similar objects (clusters) that exist in lower dimensional subspaces from a high dimensional dataset. It has a wide range of applications, such as analysing high dimensional sensor data or DNA…

Machine Learning · Computer Science 2018-11-08 Minh Tuan Doan , Jianzhong Qi , Sutharshan Rajasegarar , Christopher Leckie

Minimum spanning trees (MSTs) provide a convenient representation of datasets in numerous pattern recognition activities. Moreover, they are relatively fast to compute. In this paper, we quantify the extent to which they are meaningful in…

Machine Learning · Statistics 2025-10-16 Marek Gagolewski , Anna Cena , Maciej Bartoszuk , Łukasz Brzozowski

Due to their conceptual simplicity, k-means algorithm variants have been extensively used for unsupervised cluster analysis. However, one main shortcoming of these algorithms is that they essentially fit a mixture of identical spherical…

Machine Learning · Computer Science 2024-02-06 Raphael Araujo Sampaio , Joaquim Dias Garcia , Marcus Poggi , Thibaut Vidal