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Epilepsy is a neurological disorder characterized by seizures and epileptic events intertwined with religious and personal beliefs since prehistoric times. This review paper explores the historical context and challenges in defining…
Network-based methods are playing an increasingly important role in drug design. Our main question in this paper was whether the efficiency of drug target proteins to spread perturbations in the human interactome is larger if the binding…
This paper applies risk analysis to medical problems, through the properties of nonlinear responses (convex or concave). It shows 1) necessary relations between the nonlinearity of dose-response and the statistical properties of the…
The term "interference" has been used to describe any setting in which one subject's exposure may affect another subject's outcome. We use causal diagrams to distinguish among three causal mechanisms that give rise to interference. The…
The concept of resilience embodies the quest towards the ability to sustain shocks, to suffer from these shocks as little as possible, for the shortest time possible, and to recover with the full functionalities that existed before the…
Purpose: Prior research has established perceived pressure and life satisfaction as important correlates of depression, yet their causal interplay remains insufficiently identified. This study aims to disentangle whether satisfaction acts…
The deterrent effect of military alliances is well documented and widely accepted. However, such work has typically assumed that alliances are exogenous. This is problematic as alliances may simultaneously influence the probability of…
The global mental health crisis is a pressing concern, with college students particularly vulnerable to rising mental health disorders. The widespread use of smartphones among young adults, while offering numerous benefits, has also been…
The human connectome at the level of fiber tracts between brain regions has been shown to differ in patients with brain disorders compared to healthy control groups. Nonetheless, there is a potentially large number of different network…
Drug Side-Effects (DSEs) have a high impact on public health, care system costs, and drug discovery processes. Predicting the probability of side-effects, before their occurrence, is fundamental to reduce this impact, in particular on drug…
Noise has both auditory and extra-auditory effects. Some of the most deleterious extra-auditory effects of noise are those leading to sleep disturbances. These disturbances seem to be related to both endogenous (physical parameters) and…
As Large Language Models (LLMs) have advanced, they have brought forth new challenges, with one of the prominent issues being LLM hallucination. While various mitigation techniques are emerging to address hallucination, it is equally…
Diamagnetism, in which the magnetisation in a medium opposes the direction of an applied magnetic field, is a weak but familiar effect in a wide class of materials. Being weak it is also a linear response to any applied field. The problem…
In order to develop more precise and functional affective applications, it is necessary to achieve a balance between the psychology and the engineering applied to emotions. Signals from the central and peripheral nervous systems have been…
Stroke is one of the leading causes of death and disability worldwide but it is believed to be highly preventable. The majority of stroke prevention focuses on targeting high-risk individuals but its is important to understand how the…
The ability to control LLMs' emulated emotional states and personality traits is essential for enabling rich, human-centered interactions in socially interactive settings. We introduce PsySET, a Psychologically-informed benchmark to…
Causal inference is widely used in various fields, such as biology, psychology and economics, etc. In observational studies, we need to balance the covariates before estimating causal effect. This study extends the one-dimensional entropy…
Flexible reconfiguration of human brain networks supports cognitive flexibility and learning. However, modulating flexibility to enhance learning requires an understanding of the relationship between flexibility and brain state. In an…
Depression is a common yet serious mental disorder that affects millions of U.S. high schoolers every year. Still, accurate diagnosis and early detection remain significant challenges. In the field of public health, research shows that…
Adverse drug reaction (ADR) is widely concerned for public health issue. In this study we propose an original approach to detect the ADRs using feature matrix and feature selection. The experiments are carried out on the drug Aspirin. Major…