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Pedigree graphs, or family trees, are typically constructed by an expensive process of examining genealogical records to determine which pairs of individuals are parent and child. New methods to automate this process take as input genetic…

Data Structures and Algorithms · Computer Science 2011-10-19 Bonnie Kirkpatrick , Yakir Reshef , Hilary Finucane , Haitao Jiang , Binhai Zhu , Richard M. Karp

We consider the NP-hard Tree Containment problem that has important applications in phylogenetics. The problem asks if a given leaf-labeled network contains a subdivision of a given leaf-labeled tree. We develop a fast algorithm for the…

Computational Complexity · Computer Science 2017-02-22 Mathias Weller

A phylogenetic tree is a graphical representation of an evolutionary history of taxa in which the leaves correspond to the taxa and the non-leaves correspond to speciations. One of important problems in phylogenetic analysis is to assemble…

Combinatorics · Mathematics 2022-02-25 Hiroshi Hirai , Yuni Iwamasa

A normal network is uniquely determined by the set of phylogenetic trees that it displays. Given a set $\mathcal{P}$ of rooted binary phylogenetic trees, this paper presents a polynomial-time algorithm that reconstructs the unique binary…

Combinatorics · Mathematics 2024-07-10 Magnus Bordewich , Simone Linz , Charles Semple

We address an open question of Francis and Steel about phylogenetic networks and trees. They give a polynomial time algorithm to decide if a phylogenetic network, N, is tree-based and pose the problem: given a fixed tree T and network N, is…

Phylogenetic networks generalise phylogenetic trees and allow for the accurate representation of the evolutionary history of a set of present-day species whose past includes reticulate events such as hybridisation and lateral gene transfer.…

Populations and Evolution · Quantitative Biology 2018-09-05 Joan Carles Pons , Charles Semple , Mike Steel

In phylogenetics, phylogenetic trees are rooted binary trees, whereas phylogenetic networks are rooted arbitrary acyclic digraphs. Edges are directed away from the root and leaves are uniquely labeled with taxa in phylogenetic networks. For…

Populations and Evolution · Quantitative Biology 2016-03-30 Andreas DM Gunawan , Bhaskar DasGupta , Louxin Zhang

Invariants for complicated objects such as those arising in phylogenetics, whether they are invariants as matrices, polynomials, or other mathematical structures, are important tools for distinguishing and working with such objects. In this…

Populations and Evolution · Quantitative Biology 2022-04-06 Joan Carles Pons , Tomás M. Coronado , Michael Hendriksen , Andrew Francis

Compatibility of unrooted phylogenetic trees is a well studied problem in phylogenetics. It asks to determine whether for a set of k input trees there exists a larger tree (called a supertree) that contains the topologies of all k input…

Discrete Mathematics · Computer Science 2014-03-03 Alexander Grigoriev , Steven Kelk , Nela Lekic

We give an algorithm that, for every fixed k, decides isomorphism of graphs of rank width at most k in polynomial time. As the clique width of a graph is bounded in terms of its rank width, we also obtain a polynomial time isomorphism test…

Discrete Mathematics · Computer Science 2015-05-15 Martin Grohe , Pascal Schweitzer

Recently, the minimum number of reticulation events that is required to simultaneously embed a collection P of rooted binary phylogenetic trees into a so-called temporal network has been characterized in terms of cherry-picking sequences.…

Populations and Evolution · Quantitative Biology 2021-04-13 Janosch Döcker , Simone Linz

Phylogenetic networks are a type of directed acyclic graph that represent how a set $X$ of present-day species are descended from a common ancestor by processes of speciation and reticulate evolution. In the absence of reticulate evolution,…

Combinatorics · Mathematics 2017-08-11 Andrew Francis , Charles Semple , Mike Steel

Semidirected networks have received interest in evolutionary biology as the appropriate generalization of unrooted trees to networks, in which some but not all edges are directed. Yet these networks lack proper theoretical study. We define…

Combinatorics · Mathematics 2024-10-14 Michael Maxfield , Jingcheng Xu , Cécile Ané

Tree-based networks are a class of phylogenetic networks that attempt to formally capture what is meant by "tree-like" evolution. A given non-tree-based phylogenetic network, however, might appear to be very close to being tree-based, or…

Populations and Evolution · Quantitative Biology 2020-01-17 Mareike Fischer , Andrew Francis

Given a graph G, we investigate the question of determining the parity of the number of homomorphisms from G to some other fixed graph H. We conjecture that this problem exhibits a complexity dichotomy, such that all parity graph…

Computational Complexity · Computer Science 2013-09-17 John Faben , Mark Jerrum

For a graph property $\Pi$, Subgraph Complementation to $\Pi$ is the problem to find whether there is a subset $S$ of vertices of the input graph $G$ such that modifying $G$ by complementing the subgraph induced by $S$ results in a graph…

Data Structures and Algorithms · Computer Science 2022-08-23 Dhanyamol Antony , Sagartanu Pal , R. B. Sandeep , R. Subashini

We identify a sufficient condition, treewidth-pliability, that gives a polynomial-time algorithm for an arbitrarily good approximation of the optimal value in a large class of Max-2-CSPs parameterised by the class of allowed constraint…

Discrete Mathematics · Computer Science 2024-01-04 Miguel Romero , Marcin Wrochna , Stanislav Živný

The graph isomorphism problem has a long history in mathematics and computer science, with applications in computational chemistry and biology, and it is believed to be neither solvable in polynomial time nor NP-complete. E. Luks proposed…

Discrete Mathematics · Computer Science 2012-09-06 Adria Alcala Mena , Francesc Rossello

Graph pattern matching is a routine process for a wide variety of applications such as social network analysis. It is typically defined in terms of subgraph isomorphism which is NP-Complete. To lower its complexity, many extensions of graph…

Databases · Computer Science 2018-04-13 Houari Mahfoud

Perfect Matching-Cut is the problem of deciding whether a graph has a perfect matching that contains an edge-cut. We show that this problem is NP-complete for planar graphs with maximum degree four, for planar graphs with girth five, for…

Combinatorics · Mathematics 2021-11-01 Valentin Bouquet , Christophe Picouleau