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We propose a new compression scheme for genomic data given as sequence fragments called reads. The scheme uses a reference genome at the decoder side only, freeing the encoder from the burdens of storing references and performing…

Information Theory · Computer Science 2023-02-10 Yotam Gershon , Yuval Cassuto

There are two major approaches for sequence labeling. One is the probabilistic gradient-based methods such as conditional random fields (CRF) and neural networks (e.g., RNN), which have high accuracy but drawbacks: slow training, and no…

Machine Learning · Computer Science 2018-11-20 Xu Sun , Shuming Ma , Yi Zhang , Xuancheng Ren

Sequence alignment supports numerous tasks in bioinformatics, natural language processing, pattern recognition, social sciences, and others fields. While the alignment of two sequences may be performed swiftly in many applications, the…

Data Structures and Algorithms · Computer Science 2021-12-06 Eloi Araujo , Luiz Rozante , Diego P. Rubert , Fabio V. Martinez

Summary: We present several recent improvements to minimap2, a versatile pairwise aligner for nucleotide sequences. Now minimap2 v2.22 can more accurately map long reads to highly repetitive regions and align through insertions or deletions…

Genomics · Quantitative Biology 2021-08-10 Heng Li

Training code-switched language models is difficult due to lack of data and complexity in the grammatical structure. Linguistic constraint theories have been used for decades to generate artificial code-switching sentences to cope with this…

Computation and Language · Computer Science 2019-09-19 Genta Indra Winata , Andrea Madotto , Chien-Sheng Wu , Pascale Fung

Traditional pairwise sequence alignment is based on matching individual samples from two sequences, under time monotonicity constraints. However, in many application settings matching subsequences (segments) instead of individual samples…

Databases · Computer Science 2016-09-28 Shahriar Shariat , Vladimir Pavlovic

Protein language models often take into consideration the alignment between a protein sequence and its textual description. However, they do not take structural information into consideration. Traditional methods treat sequence and…

Machine Learning · Computer Science 2026-03-10 Aditya Ranganath , Hasin Us Sami , Kowshik Thopalli , Bhavya Kailkhura , Wesam Sakla

Online alignment in machine translation refers to the task of aligning a target word to a source word when the target sequence has only been partially decoded. Good online alignments facilitate important applications such as lexically…

Computation and Language · Computer Science 2022-04-05 Soumya Chatterjee , Sunita Sarawagi , Preethi Jyothi

We are now witnessing significant progress of deep learning methods in a variety of tasks (or datasets) of proteins. However, there is a lack of a standard benchmark to evaluate the performance of different methods, which hinders the…

Machine Learning · Computer Science 2022-09-20 Minghao Xu , Zuobai Zhang , Jiarui Lu , Zhaocheng Zhu , Yangtian Zhang , Chang Ma , Runcheng Liu , Jian Tang

This work proposes a multi-image matching method to estimate semantic correspondences across multiple images. In contrast to the previous methods that optimize all pairwise correspondences, the proposed method identifies and matches only a…

Computer Vision and Pattern Recognition · Computer Science 2018-05-02 Qianqian Wang , Xiaowei Zhou , Kostas Daniilidis

Copy mechanisms are employed in sequence to sequence models (seq2seq) to generate reproductions of words from the input to the output. These frameworks, operating at the lexical type level, fail to provide an explicit alignment that records…

Computation and Language · Computer Science 2020-10-30 Abhinav Singh , Patrick Xia , Guanghui Qin , Mahsa Yarmohammadi , Benjamin Van Durme

We propose a method of aligning a source image to a target image, where the transform is specified by a dense vector field. The two images are encoded as feature hierarchies by siamese convolutional nets. Then a hierarchy of aligner modules…

Computer Vision and Pattern Recognition · Computer Science 2019-04-05 Eric Mitchell , Stefan Keselj , Sergiy Popovych , Davit Buniatyan , H. Sebastian Seung

There now exist compact indexes that can efficiently list all the occurrences of a pattern in a dataset consisting of thousands of genomes, or even all the occurrences of all the pattern's maximal exact matches (MEMs) with respect to the…

Data Structures and Algorithms · Computer Science 2022-09-20 Adrián Goga , Andrej Baláž , Alessia Petescia , Travis Gagie

We define a mapping from transition-based parsing algorithms that read sentences from left to right to sequence labeling encodings of syntactic trees. This not only establishes a theoretical relation between transition-based parsing and…

Computation and Language · Computer Science 2020-11-03 Carlos Gómez-Rodríguez , Michalina Strzyz , David Vilares

We study the problem of aligning multiple sequences with the goal of finding an alignment that either maximizes the number of aligned symbols (the longest common subsequence (LCS)), or minimizes the number of unaligned symbols (the…

Data Structures and Algorithms · Computer Science 2021-10-26 Debarati Das , Barna Saha

Long reads produced by third-generation sequencing technologies are used to construct an assembly (i.e., the subject's genome), which is further used in downstream genome analysis. Unfortunately, long reads have high sequencing error rates…

Genomics · Quantitative Biology 2020-10-29 Can Firtina , Jeremie S. Kim , Mohammed Alser , Damla Senol Cali , A. Ercument Cicek , Can Alkan , Onur Mutlu

In this paper, we present an optical computing method for string data alignment applicable to genome information analysis. By applying moire technique to spatial encoding patterns of deoxyribonucleic acid (DNA) sequences, association…

A new set of DNA base-nucleic acid codes and their hypercomplex number representation have been introduced for taking the probability of each nucleotide into full account. A new scoring system has been proposed to suit the hypercomplex…

Other Quantitative Biology · Quantitative Biology 2014-03-12 Jian-Jun Shu , Li Shan Ouw

To solve time inefficiency issue, only potential pairs are compared in string-matching-based source code plagiarism detection; wherein potentiality is defined through a fast-yet-order-insensitive similarity measurement (adapted from…

Software Engineering · Computer Science 2018-10-30 Oscar Karnalim , Lisan Sulistiani

Many robotics applications require alignment and fusion of observations obtained at multiple views to form a global model of the environment. Multi-way data association methods provide a mechanism to improve alignment accuracy of pairwise…

Robotics · Computer Science 2020-03-06 Kaveh Fathian , Kasra Khosoussi , Yulun Tian , Parker Lusk , Jonathan P. How
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