Related papers: Pyro-Align: Sample-Align based Multiple Alignment …
Multi-choice reading comprehension is a challenging task, which involves the matching between a passage and a question-answer pair. This paper proposes a new co-matching approach to this problem, which jointly models whether a passage can…
In this paper we report on an algorithm for aligning multiple protein structures. The algorithm has been tested on a variety of inputs and it performs well in comparison to well-known algorithms for this problem.
Ancestral sequence reconstruction is a key task in computational biology. It consists in inferring a molecular sequence at an ancestral species of a known phylogeny, given descendant sequences at the tip of the tree. In addition to its many…
Probabilistic Programming Languages (PPLs) allow users to encode statistical inference problems and automatically apply an inference algorithm to solve them. Popular inference algorithms for PPLs, such as sequential Monte Carlo (SMC) and…
Adapted from biological sequence alignment, trace alignment is a process mining technique used to visualize and analyze workflow data. Any analysis done with this method, however, is affected by the alignment quality. The best existing…
A new set of DNA base-nucleic acid codes and their hypercomplex number representation have been introduced for taking the probability of each nucleotide into full account. A new scoring system has been proposed to suit the hypercomplex…
We describe an new algorithm for visualizing an alignment of biological sequences according to a probabilistic model of evolution. The resulting data array is readily interpreted by the human eye and amenable to digital image techniques. We…
Word alignment which aims to extract lexicon translation equivalents between source and target sentences, serves as a fundamental tool for natural language processing. Recent studies in this area have yielded substantial improvements by…
Conversational Machine Reading (CMR) requires answering a user's initial question through multi-turn dialogue interactions based on a given document. Although there exist many effective methods, they largely neglected the alignment between…
Extending large language models to effectively handle long contexts requires instruction fine-tuning on input sequences of similar length. To address this, we present LongAlign -- a recipe of the instruction data, training, and evaluation…
The alignment problem in Large Language Models (LLMs) involves adapting them to the broad spectrum of human values. This requirement challenges existing alignment methods due to diversity of preferences and regulatory standards. This paper…
Large language models (LLMs) can handle a wide variety of general tasks with simple prompts, without the need for task-specific training. Multimodal Large Language Models (MLLMs), built upon LLMs, have demonstrated impressive potential in…
Background: Alignment of biological sequences such as DNA, RNA or proteins is one of the most widely used tools in computational bioscience. All existing alignment algorithms rely on heuristic scoring schemes based on biological expertise.…
Pyro is a probabilistic programming language built on Python as a platform for developing advanced probabilistic models in AI research. To scale to large datasets and high-dimensional models, Pyro uses stochastic variational inference…
Text alignment finds application in tasks such as citation recommendation and plagiarism detection. Existing alignment methods operate at a single, predefined level and cannot learn to align texts at, for example, sentence and document…
In process mining, alignments quantify the degree of deviation between an observed event trace and a business process model and constitute the most important conformance checking technique. We study the algorithmic complexity of computing…
Large language models require continuous adaptation to new tasks while preserving safety alignment. However, fine-tuning on even benign data often compromises safety behaviors, including refusal of harmful requests, truthfulness, and…
Large Language Models (LLMs) acquire extensive knowledge and remarkable abilities from extensive text corpora, making them powerful tools for various applications. To make LLMs more usable, aligning them with human preferences is essential.…
Multiple Sequence Alignment (MSA) is one of the most computationally intensive tasks in Computational Biology. Existing best known solutions for multiple sequence alignment take several hours (in some cases days) of computation time to…
Sequence alignment supports numerous tasks in bioinformatics, natural language processing, pattern recognition, social sciences, and others fields. While the alignment of two sequences may be performed swiftly in many applications, the…