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Mechanical cues from the extracellular microenvironment play a central role in regulating the structure, function and fate of living cells. Nevertheless, the precise nature of the mechanisms and processes underlying this crucial cellular…

Biological Physics · Physics 2015-06-23 Ariel Livne , Eran Bouchbinder , Benjamin Geiger

Prestress in amorphous solids bears the memory of their formation, and plays a profound role in their mechanical properties, from stiffening or softening elastic moduli to shifting frequencies of vibrational modes, as well as directing…

Soft Condensed Matter · Physics 2021-10-15 Shang Zhang , Ethan Stanifer , Vishwas Vasisht , Leyou Zhang , Emanuela Del Gado , Xiaoming Mao

In a co-evolutionary context, the survive probability of individual elements of a system depends on their relation with their neighbors. The natural selection process depends on the whole population, which is determined by local events…

Biological Physics · Physics 2009-11-13 Juan G. Diaz Ochoa

Quantifying the outcomes of cells collisions is a crucial step in building the foundations of a kinetic theory of living matter. Here, we develop a mechanical theory of such collisions by first representing individual cells as extended…

Biological Physics · Physics 2019-12-11 Pierre Recho , Thibaut Putelat , Lev Truskinovsky

A number of studies have concluded that dreaming is mostly caused by randomly arriving internal signals because "dream contents are random impulses", and argued that dream sleep is unlikely to play an important part in our intellectual…

Neurons and Cognition · Quantitative Biology 2026-02-05 Qi Zhang

Protocol-dependent states in structural glasses can encode a disordered, yet retrievable memory. While training such materials is typically done via a global drive, such as external shear, in dense active matter the driving is instead local…

Soft Condensed Matter · Physics 2024-04-05 Elisabeth Agoritsas , Peter K. Morse

Disordered solids often change their elastic response as they slowly age. Using experiments and simulations, we study how aging disordered planar networks under an applied stress affects their nonlinear elastic response. We are able to…

Soft Condensed Matter · Physics 2020-11-18 Daniel Hexner , Nidhi Pashine , Andrea J. Liu , Sidney R. Nagel

Local anaxonic neurons with graded potential release are important ingredients of nervous systems, present in the olfactory bulb system of mammalians, in the human visual system, as well as in arthropods and nematodes. We develop a neuronal…

Neurons and Cognition · Quantitative Biology 2021-04-14 M. Rahimi-Majd , M. A. Seifi , L. de Arcangelis , M. N. Najafi

Learning arguably involves the discovery and memorization of abstract rules. The aim of this paper is to study associative memory mechanisms. Our model is based on high-dimensional matrices consisting of outer products of embeddings, which…

Machine Learning · Statistics 2024-02-22 Vivien Cabannes , Elvis Dohmatob , Alberto Bietti

The neural network is a powerful computing framework that has been exploited by biological evolution and by humans for solving diverse problems. Although the computational capabilities of neural networks are determined by their structure,…

Neural and Evolutionary Computing · Computer Science 2019-03-27 Nathaniel Rodriguez , Eduardo Izquierdo , Yong-Yeol Ahn

In an equilibrium thermal environment, random elastic collisions between background particles and a tracer establish the picture of Brownian motion fulfilling the celebrated Einstein relation between diffusivity and mobility. In nature,…

Thanks to recent technological advances, it is now possible to track with an unprecedented precision and for long periods of time the movement patterns of many living organisms in their habitat. The increasing amount of data available on…

Populations and Evolution · Quantitative Biology 2015-05-19 Denis Boyer , Peter D. Walsh

Biological cells are often found to sense their chemical environment near the single-molecule detection limit. Surprisingly, this precision is higher than simple estimates of the fundamental physical limit, hinting towards active sensing…

Biological Physics · Physics 2015-11-06 Gerardo Aquino , Luke Tweedy , Doris Heinrich , Robert G. Endres

The initiation of directional cell motion requires symmetry breaking that can happen both with or without external stimuli. During cell crawling, forces generated by the cytoskeleton and their transmission through mechanosensitive adhesions…

Cell Behavior · Quantitative Biology 2023-06-02 Yuzhu Chen , David Saintillan , Padmini Rangamani

The mechanisms underlying major aspects of the human brain remain a mystery. It is unknown how verbal episodic memory is formed and integrated with sensory episodic memory. There is no consensus on the function and nature of dreaming. Here…

Other Quantitative Biology · Quantitative Biology 2013-06-26 Xiaoqiu Huang

We discuss the plastic behavior of an amorphous matrix reinforced by hard particles. A mesoscopic depinning-like model accounting for Eshelby elastic interactions is implemented. Only the effect of a plastic disorder is considered.…

Materials Science · Physics 2016-02-17 Botond Tyukodi , Claire A. Lemarchand , Jesper S. Hansen , Damien Vandembroucq

It is shown that due to memory effects the complex behaviour of components in a stochastic system can be transmitted to macroscopic evolution of the system as a whole. Within the Markov approximation widely using in ordinary statistical…

adap-org · Physics 2009-10-30 A. A. Stanislavsky

Cellular form and function emerge from complex mechanochemical systems within the cytoplasm. No systematic strategy currently exists to infer large-scale physical properties of a cell from its many molecular components. This is a…

Lack of memory (locality in time) is a major limitation of almost all present time-dependent density functional approximations. By using semiclassical dynamics to compute correlation effects within a density-matrix functional approach, we…

Chemical Physics · Physics 2015-05-18 A. K. Rajam , I. Raczkowska , N. T. Maitra

Albeit epidemic models have evolved into powerful predictive tools for the spread of diseases and opinions, most assume memoryless agents and independent transmission channels. We develop an infection mechanism that is endowed with memory…

Physics and Society · Physics 2019-05-22 Xavier R. Hoffmann , Marián Boguñá
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