Related papers: The role of the extra cellular matrix on memory
In this doctoral thesis, we investigate the complex interplay between temporal dynamics associated with aging and memory and their effects on social and economic systems. To do so, we combine theoretical modeling, to explore the aging…
We present a minimal continuum model of strongly adhering cells as active contractile isotropic media and use the model to study the effect of the geometry of the adhesion patch in controlling the spatial distribution of traction and…
Declarative memory, the memory that can be "declared" in words or languages, is made up of two dissociated parts: episodic memory and semantic memory. This dissociation has its neuroanatomical basis episodic memory is mostly associated with…
Networks of neurons in some brain areas are flexible enough to encode new memories quickly. Using a standard firing rate model of recurrent networks, we develop a theory of flexible memory networks. Our main results characterize networks…
Game theory is fundamental to understanding cooperation between agents. Mainly, the Prisoner's Dilemma is a well-known model that has been extensively studied in complex networks. However, although the emergence of cooperation has been…
Network systems can exhibit memory effects in which the interactions between different pairs of nodes adapt in time, leading to the emergence of preferred connections, patterns, and sub-networks. To a first approximation, this memory can be…
The mechanosensitivity of cells, which determines how they are able to respond to mechanical signals received from their environment, is crucial for the functioning of all biological systems. In experiments, cells placed on cyclically…
The discovery of neural plasticity has proved that throughout the life of a human being, the brain reorganizes itself through forming new neural connections. The formation of new neural connections are achieved through the brain's effort to…
Despite substantial research into the biological basis of memory, the precise mechanisms by which experiences are encoded, stored, and retrieved in the brain remain incompletely understood. A growing body of evidence supports the engram…
Passive elastic elements can contribute to stability, energetic efficiency, and impact absorption in both biological and robotic systems. They also add dynamical complexity which makes them more challenging to model and control. The impact…
We examine the dynamical evolution of the state of a neurone, with particular care to the non-equilibrium nature of the forces influencing its movement in state space. We combine non-equilibrium statistical mechanics and dynamical systems…
The brain consists not only of neurons but also of non-neuronal cells, including astrocytes. Recent discoveries in neuroscience suggest that astrocytes directly regulate neuronal activity by releasing gliotransmitters such as glutamate. In…
This paper deals with different models of random walks with a reinforced memory of preferential attachment type. We consider extensions of the Elephant Random Walk introduced by Sch\"utz and Trimper [2004] with a stronger reinforcement…
This paper discusses the evolution of probability distributions for certain time-dependent dynamical systems. Exponential loss of memory is proved for expanding maps and for one-dimensional piecewise expanding maps with slowly varying…
We study the effect of imperfect memory on decision making in the context of a stochastic sequential action-reward problem. An agent chooses a sequence of actions which generate discrete rewards at different rates. She is allowed to make…
What is the physiological basis of long-term memory? The prevailing view in neuroscience attributes changes in synaptic efficacy to memory acquisition. This view implies that stable memories correspond to stable connectivity patterns.…
Migrating cells exhibit various motility patterns, resulting from different migration mechanisms, cell properties, or cell-environment interactions. The complexity of cell dynamics is reflected, e.g., in the diversity of the observed forms…
It is widely accepted that the hippocampal place cells' spiking activity produces a cognitive map of space. However, many details of this representation's physiological mechanism remain unknown. For example, it is believed that the place…
The action potential is widely considered a purely electrical phenomenon. However, one also finds mechanical and thermal changes that can be observed experimentally. In particular, nerve membranes become thicker and axons contract. The…
When we encounter a new person or place, we may easily encode it into our memories, or we may quickly forget it. Recent work finds that this likelihood of encoding a given entity - memorability - is highly consistent across viewers and…