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We derive the optimal estimates of the free energies of an arbitrary number of thermodynamic states from nonequilibrium work measurements; the work data are collected from forward and reverse switching processes and obey a fluctuation…

Statistical Mechanics · Physics 2009-11-11 Paul Maragakis , Martin Spichty , Martin Karplus

Brownian dynamics simulations are used to study the detachment of a particle from a substrate. Although the model is simple and generic, we attempt to map its energy, length and time scales onto a specific experimental system, namely a bead…

Soft Condensed Matter · Physics 2021-01-08 Emma Hodges , B. M. Cooke , E. M. Sevick , Debra J. Searles , B. Duenweg , J. Ravi Prakash

A fluctuation theorem relating the work to its optimal average work is presented. The function mediating the relation is increasing and convex, and depends on the switching time $\tau$, driving strength $\delta\lambda/\lambda_0$, and…

Statistical Mechanics · Physics 2024-07-02 Pierre Nazé

Generative models are a promising tool to address the sampling problem in multi-body and condensed-matter systems in the framework of statistical mechanics. In this work, we show that normalizing flows can be used to learn a transformation…

Computational Physics · Physics 2022-08-23 Alessandro Coretti , Sebastian Falkner , Phillip Geissler , Christoph Dellago

Nonequilibrium systems exchange the energy with an environment in the form of work and heat. The work done on a system obeys the fluctuation theorem, while the dissipated heat which differs from the work by the internal energy change does…

Statistical Mechanics · Physics 2014-02-04 Jae Dong Noh

The free-energy difference $\Delta F$ between two high-dimensional systems is notoriously difficult to compute, but very important for many applications, such as drug discovery. We demonstrate that an unconventional definition of work…

Soft Condensed Matter · Physics 2024-10-24 Adrianne Zhong , Benjamin Kuznets-Speck , Michael R. DeWeese

Given a probability density $P({\bf x}|{\boldsymbol \lambda})$, where $\bf x$ represents continuous degrees of freedom and $\lambda$ a set of parameters, it is possible to construct a general identity relating expectations of observable…

Statistical Mechanics · Physics 2021-01-12 Sergio Davis , Gonzalo Gutiérrez

Diverse physical systems are characterized by their response to small perturbations. Near thermodynamic equilibrium, the fluctuation-dissipation theorem provides a powerful theoretical and experimental tool to determine the nature of…

Statistical Mechanics · Physics 2020-03-25 Jeremy A. Owen , Todd R. Gingrich , Jordan M. Horowitz

A fluctuation relation, which is an extended form of the Jarzynski equality, is introduced and discussed. We show how to apply this relation in order to evaluate the free energy landscape of simple systems. These systems are manipulated by…

Statistical Mechanics · Physics 2007-05-23 A. Imparato , L. Peliti

Fluctuation theorems impose constraints on possible work extraction probabilities in thermodynamical processes. These constraints are stronger than the usual second law, which is concerned only with average values. Here, we show that such…

Quantum Physics · Physics 2020-02-21 Paul Boes , Rodrigo Gallego , Nelly H. Y. Ng , Jens Eisert , Henrik Wilming

We study experimentally the thermal fluctuations of energy input and dissipation in a harmonic oscillator driven out of equilibrium, and search for Fluctuation Relations. We study transient evolution from the equilibrium state, together…

Statistical Mechanics · Physics 2007-11-28 Sylvain Joubaud , Nicolas Garnier , Sergio Ciliberto

The fluctuation-dissipation theorem is a fundamental result in statistical physics that establishes a connection between the response of a system subject to a perturbation and the fluctuations associated with observables in equilibrium.…

Quantum Physics · Physics 2022-08-03 Tanmoy Biswas , A. de Oliveira Junior , Michał Horodecki , Kamil Korzekwa

The fluctuation-dissipation theorem is a cornerstone result in statistical mechanics that can be used to translate the statistics of the free natural variability of a system into information on its forced response to perturbations. By…

Statistical Mechanics · Physics 2025-06-19 Niccolò Zagli , Matthew Colbrook , Valerio Lucarini , Igor Mezić , John Moroney

The probability distribution of the entropy production for the effusion of an ideal gas between two compartments is calculated explicitly. The fluctuation theorem is verified. The analytic results are in good agreement with numerical data…

Statistical Mechanics · Physics 2007-05-23 B. Cleuren , C. Van den Broeck , R. Kawai

We elucidate the connection between various fluctuation theorems by a microcanonical version of the Crooks relation. We derive the microscopically exact expression for the work distribution in an idealized Joule experiment, namely for an…

Statistical Mechanics · Physics 2007-05-23 B. Cleuren , C. Van den Broeck , R. Kawai

Information maximization has been investigated as a possible mechanism of learning governing the self-organization that occurs within the neural systems of animals. Within the general context of models of neural systems bidirectionally…

Disordered Systems and Neural Networks · Physics 2015-11-18 Takashi Hayakawa , Toshio Aoyagi

Global equilibrium fragmentation inside a freeze out constraining volume is a working hypothesis widely used in nuclear fragmentation statistical models. In the framework of classical Lennard Jones molecular dynamics, we study how the…

Nuclear Theory · Physics 2009-11-10 A. Chernomoretz , F. Gulminelli , M. J. Ison , C. O. Dorso

In this paper, we study Jarzynski's equality and fluctuation theorems for diffusion processes. While some of the results considered in the current work are known in the (mainly physics) literature, we review and generalize these…

Mathematical Physics · Physics 2019-04-09 Carsten Hartmann , Christof Schuette , Wei Zhang

By measuring a linear response function directly, such as the dynamic susceptibility, one can understand fundamental material properties. However, a fresh perspective can be offered by studying fluctuations. This can be related back to the…

Strongly Correlated Electrons · Physics 2021-05-04 L. Shen , M. Seaberg , E. Blackburn , J. J. Turner

We combine theoretical and experimental efforts to propose a method for studying energy fluctuations, in particular, to obtain the related bi-stochastic matrix of transition probabilities by means of simple measurements at the end of a…

Quantum Physics · Physics 2021-07-21 Marcela Herrera , John P. S. Peterson , Roberto M. Serra , Irene D'Amico
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