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The theory of generalized locally Toeplitz (GLT) sequences is a powerful apparatus for computing the asymptotic spectral distribution of matrices $A_n$ arising from numerical discretizations of differential equations. Indeed, when the mesh…
For any family of $N\times N$ random matrices $(\mathbf{A}_k)_{k\in K}$ which is invariant, in law, under unitary conjugation, we give general sufficient conditions for central limit theorems for random variables of the type…
We extend recent methods for parametric sequence alignment to the parameter space for scoring RNA folds. This involves the construction of an RNA polytope. A vertex of this polytope corresponds to RNA secondary structures with common…
The regulation of cellular function is often controlled at the level of gene transcription. Such genetic regulation usually consists of interacting networks, whereby gene products from a single network can act to control their own…
We consider the asymptotics of the partition function of the extended Gross-Witten-Wadia unitary matrix model by introducing an extra logarithmic term in the potential. The partition function can be written as a Toeplitz determinant with…
The way tension propagates along a chain is a key to govern many of anomalous dynamics in macromolecular systems. After introducing the weak and the strong force regimes of the tension propagation, we focus on the latter, in which the…
We propose an asymptotic expansion formula for matrix integrals, including oscillatory terms (derivatives of theta-functions) to all orders. This formula is heuristically derived from the analogy between matrix integrals, and formal matrix…
Myriad viruses use positive-strand RNA molecules as their genomes. Far from being only a repository of genetic material, viral RNA performs numerous other functions mediated by its physical structure and chemical properties. In this…
We present an unified approach on the behavior of two random growth models (external DLA and internal DLA) on infinite graphs, the second one being an internal counterpart of the first one. Even though the two models look pretty similar,…
It has been suggested that scattering cross sections at very high energies for producing large numbers of Higgs particles may exhibit factorial growth, and that curing this growth might be relevant to other questions in the Standard Model.…
This paper discusses the enumeration of two-terminal series-parallel networks, i.e. the number of electrical networks built with n identical elements connected in series or parallel with two-terminal nodes. They frequently occur in applied…
A model is presented relating the evolution of genomic GC content over time to AT$\rightarrow$GC and GC$\rightarrow$AT mutation rates. By employing It\^o calculus it is shown that if mutation rates in asexually reproducing organisms are…
We study a system of random walks, known as the frog model, starting from a profile of independent Poisson($\lambda$) particles per site, with one additional active particle planted at some vertex $\mathbf{o}$ of a finite connected simple…
We train a neural network to predict distributional responses in gene expression following genetic perturbations. This is an essential task in early-stage drug discovery, where such responses can offer insights into gene function and inform…
In this paper we study a 2-type linear-fractional branching process in varying environment with asymptotically constant mean matrices. Let $\nu$ be the extinction time and for $k\ge1$ let $M_k$ be the mean matrix of offspring distribution…
Background: Neutron stars are astronomical systems with nucleons submitted to extreme conditions. Due to the long range coulomb repulsion between protons, the system has structural inhomogeneities. These structural inhomogeneities arise…
We propose a generic model of driven DNA under the influence of an oscillatory force of amplitude $F$ and frequency $\nu$ and show the existence of a dynamical transition for a chain of finite length. We find that the area of the hysteresis…
We consider GL_n(F_q)-analogues of certain factorization problems in the symmetric group S_n: rather than counting factorizations of the long cycle (1, 2, ..., n) given the number of cycles of each factor, we count factorizations of a…
As a consequence of the rugged landscape of RNA molecules their folding is described by the kinetic partitioning mechanism according to which only a small fraction ($\phi_F$) reaches the folded state while the remaining fraction of…
We study the asymptotic behavior of the partition function and the correlation kernel in random matrix ensembles of the form $\frac{1}{Z_n} \big|\det \big( M^2-tI \big)\big|^{\alpha} e^{-n\operatorname{Tr} V(M)}dM$, where $M$ is an $n\times…