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As soon as the first particles emerge from an ion source, the source characteristics need to be determined. The total beam intensity, the transverse particle distributions, the beam divergence and emittance as well as the longitudinal…

Accelerator Physics · Physics 2014-04-03 U. Raich

For efficient application of protons and light ions in radiotherapy, detailed knowledge and realistic models of the corresponding radiobiological mechanism are necessary. Basic characteristics of this mechanism have been represented within…

Biological Physics · Physics 2007-05-23 Pavel Kundrat , Hana Hromcikova , Milos Lokajicek

Biological effectiveness of a certain absorbed dose of ionizing radiation depends on the radiation quality, i. e. the spectrum of ionizing particles and their energy distribution. As has been shown in several studies, the biological…

Medical Physics · Physics 2021-11-24 Hans Rabus

One of the most progressive methods of cancer treatment is ion beam therapy. The simulations of water radiolysis show that in the cell medium the most long-living species are hydrogen peroxide (H$_2$O$_2$) molecules. But up to the present…

Biological Physics · Physics 2019-08-08 Oleksii Zdorevskyi , Sergey N. Volkov

The radiation-induced damages in bio-molecules are ubiquitous processes in radiotherapy, radio-biology and critical to space-projects. In this study we present a precise quantification of the fragmentation mechanisms of deoxyribonucleic…

Biological Physics · Physics 2022-01-28 Santosh KC , Ramin Abolfath

Radiation damage is an unavoidable process when performing structural investigations of biological macromolecules with X-ray sources. In crystallography this process can be limited through damage distribution in a crystal, while for single…

Materials Science · Physics 2009-11-13 C. Caleman , C. Ortiz , E. Marklund , F. Bultmark , M. Gabrysch , F. G. Parak , J. Hajdu , M. Klintenberg , N. Timneanu

Molecular collisions can be studied at very low relative kinetic energies, in the milliKelvin range, by merging codirectional beams with much higher translational energies, extending even to the kiloKelvin range, provided that the beam…

Chemical Physics · Physics 2015-06-05 Qi Wei , Igor Lyuksyutov , Dudley Herschbach

Over the past decade, experimental microscopy and spectroscopy have made significant progress in the study of the morphological, optical, electronic and transport properties of materials. These developments include higher spatial…

Materials Science · Physics 2025-02-12 Simone Taioli , Maurizio Dapor

The photon-ion merged-beams technique for the photoionization of mass/charge selected ionized atoms, molecules and clusters by x-rays from synchrotron radiation sources is introduced. Examples for photoionization of atomic ions are…

Atomic Physics · Physics 2017-02-22 S. Schippers , A. L. D. Kilcoyne , R. A. Phaneuf , A. Müller

Raman spectroscopy can be used to identify molecules such as DNA by the characteristic scattering of light from a laser. It is sensitive at very low concentrations and can accurately quantify the amount of a given molecule in a sample. The…

Applications · Statistics 2026-02-03 Matthew Moores , Kirsten Gracie , Jake Carson , Karen Faulds , Duncan Graham , Mark Girolami

Beam damage is a major limitation in electron microscopy that becomes increasingly severe at higher resolution. One possible route to circumvent radiation damage, which forms the basis for single-particle electron microscopy and related…

Investigating the interaction of electron beams with materials and light has been a field of research since more than a century. The field was advanced theoretically by the raise of quantum mechanics and technically by the introduction of…

Optics · Physics 2017-10-11 Nahid Talebi

Particle therapy is a well established clinical treatment of tumors. More than one hundred particle therapy centers are in operation world wide. The advantage of using hadrons like protons or carbon ions as particles for tumor irradiation…

Nowadays there is a growing interest in Particle Therapy treatments exploiting light ion beams against tumors due to their enhanced Relative Biological Effectiveness and high space selectivity. In particular promising results are obtained…

Ionic liquid ion sources are a promising technology that can be used for many applications from space propulsion to focused ion beam microetching. Ionic liquid ion sources produce ion beams by extracting single ions and metastable solvated…

Chemical Physics · Physics 2021-11-17 Madeleine Schroeder

Focused ion beam irradiation of metastable Fe$_{78}$Ni$_{22}$ thin films grown on Cu(100) substrates is used to create ferromagnetic, body-centered-cubic patterns embedded into paramagnetic, face-centered-cubic surrounding. The structural…

Using atomistic computer simulations, we study how ion irradiation can be used to alter the morphology of a graphene monolayer by introducing defects of specific type, and to cut graphene sheets. Based on the results of our analytical…

Materials Science · Physics 2011-03-22 O. Lehtinen , J. Kotakoski , A. V. Krasheninnikov , J. Keinonen

Focused ion beam milling allows manipulation of the shape and size of nanostructures to create geometries potentially useful for opto-electronics, thermoelectrics, and quantum computing. We focus on using the ion beam to control the…

Materials Science · Physics 2017-10-20 Sarah Friedensen , Jerome T. Mlack , Marija Drndić

Electron beam ion sources (EBISs) are ion sources that work based on the principle of electron impact ionization, allowing the production of very highly charged ions. The ions produced can be extracted as a DC ion beam as well as ion pulses…

Accelerator Physics · Physics 2014-10-30 G. Zschornacka , M. Schmidt , A. Thorn

Optical microresonators have proven powerful in a wide range of applications, including cavity quantum electrodynamics, biosensing, microfludics, and cavity optomechanics. Their performance depends critically on the exact distribution of…