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We investigate the influence of varying confinement on the dynamics of polymer translocation through a cone shaped channel. For this, a linear polymer chain is modeled by a self voiding walks (SAWs) on a square lattice. The cis-side of a…

Soft Condensed Matter · Physics 2024-01-10 Manish Dwivedi , Sumitra Rudra , Sanjay Kumar

The impact of thermal fluctuations on the translocation dynamics of a polymer chain driven through a narrow pore has been investigated theoretically and by means of extensive Molecular-Dynamics (MD) simulation. The theoretical consideration…

Soft Condensed Matter · Physics 2015-06-12 J. L. A. Dubbeldam , V. G. Rostiashvili , A. Milchev , T. A. Vilgis

We study the translocation of a semiflexible polymer through extended pores with patterned stickiness, using Langevin dynamics simulations. We find that the consequence of pore patterning on the translocation time dynamics is dramatic and…

Soft Condensed Matter · Physics 2018-05-02 Rajneesh Kumar , Abhishek Chaudhuri , Rajeev Kapri

We study translocation dynamics of a driven compressible semi-flexible chain consisting of alternate blocks of stiff ($S$) and flexible ($F$) segments of size $m$ and $n$ respectively for different chain length $N$ in two dimension (2D).…

Biological Physics · Physics 2015-06-19 Ramesh Adhikari , Aniket Bhattacharya

Liquid transport through nanopore is central into many applications, from water purification to biosensing or energy harvesting. Ultimately thin nanopores are of major interest in these applications to increase driving potential and reduce…

Fluid Dynamics · Physics 2020-10-05 Olivier Liot , Catherine Sempere , Christophe Ybert , Anne-Laure Biance

We investigate the dynamics of pore-driven polymer translocation by theoretical analysis and molecular dynamics (MD) simulations. Using the tension propagation theory within the constant flux approximation we derive an explicit equation of…

Soft Condensed Matter · Physics 2015-06-23 Jalal Sarabadani , Timo Ikonen , Tapio Ala-Nissila

We present a detailed description of biopolymer translocation through a nanopore in the presence of a solvent, using an innovative multi-scale methodology which treats the biopolymer at the microscopic scale as combined with a…

Computational Physics · Physics 2008-02-27 Massimo Bernaschi , Simone Melchionna , Sauro Succi , Maria Fyta , Efthimios Kaxiras

Inspired by its central role in many biological processes, the transport of biopolymers across nanoscale pores is at the heart of a single-molecule sensing technology aimed at nucleic acid and protein sequencing, as well as biomarker…

Biological Physics · Physics 2025-10-16 Martin Charron , Breeana Elliott , Nada Kerrouri , Liqun He , Vincent Tabard-Cossa

The advent of solid state nanodevices allows for interrogating the physico-chemical properties of a polyelectrolyte chain by electrophoretically driving it through a nanopore. Salient dynamical aspects of the translocation process have been…

Soft Condensed Matter · Physics 2015-06-05 A. Rosa , M. Di Ventra , C. Micheletti

Polymer translocation through a nano-pore in a thin membrane is studied using a coarse-grained bead-spring model and Langevin dynamics simulation with a particular emphasis to explore out of equilibrium characteristics of the translocating…

Soft Condensed Matter · Physics 2015-05-14 Aniket Bhattacharya , Kurt Binder

In the approach of biomolecules to a nanopore, it is essential to capture the effects of hydrodynamic anisotropy of the molecules and the near-wall hydrodynamic interactions which hinder their diffusion. We present a detailed theoretical…

Soft Condensed Matter · Physics 2020-12-09 Radost Waszkiewicz , Maciej Lisicki

In recent years polymer translocation, i.e., transport of polymeric molecules through nanometer-sized pores and channels embedded in membranes, has witnessed strong advances. It is now possible to observe single-molecule polymer dynamics…

Soft Condensed Matter · Physics 2013-09-13 Debabrata Panja , Gerard T. Barkema , Anatoly B. Kolomeisky

Translocation dynamics of an active semi-flexible polymer through a nano-pore into a rigid two dimensional circular cavity, and the polymer packing dynamics have been studied by using Langevin dynamics (LD) simulations. The results show…

Soft Condensed Matter · Physics 2022-11-15 Amir Rezaie-Dereshgi , Hamidreza Khalilian , Jalal Sarabadani

We consider single particle and polymer translocation where the frictional properties experienced from the environment are changing in time. This work is motivated by the interesting frequency responsive behaviour observed when a polymer is…

Soft Condensed Matter · Physics 2012-12-06 Jack A. Cohen , Abhishek Chaudhuri , Ramin Golestanian

We consider the dynamics of polymer translocation out of confined environments. Analytic scaling arguments lead to the prediction that the translocation time scales like $\tau\sim N^{\beta+\nu_{2D}}R^{1+(1-\nu_{2D})/\nu}$ for translocation…

Soft Condensed Matter · Physics 2009-08-11 Kaifu Luo , Ralf Metzler , Tapio Ala-Nissila , See-Chen Ying

We investigate by Monte Carlo simulations the zipping and unzipping dynamics of two polymers connected by one end and subject to an attractive interaction between complementary monomers. In zipping, the polymers are quenched from a high…

Soft Condensed Matter · Physics 2011-02-15 Alessandro Ferrantini , Enrico Carlon

We construct a new statistical physical model of polymer translocation through a pore in a membrane treated as the diffusion process across a free energy barrier. We determine the translocation time in terms of chain flexibility yielding an…

Soft Condensed Matter · Physics 2015-06-25 W. Sung , P. J. Park

We consider the translocation of a one-dimensional polymer through a pore channel helped by a motor driven by a dichotomous noise with time exponential correlation. We are interested in the study of the translocation time, mean velocity and…

Soft Condensed Matter · Physics 2012-03-01 Alessandro Fiasconaro , Juan José Mazo , Fernando Falo

We investigate the translocation of rods with different charge distributions using hybrid Langevin Dynamics and Lattice Boltzmann (LD-LB) simulations. Electrostatic interactions are added to the system using the $P^3M$ algorithm to model…

Soft Condensed Matter · Physics 2022-05-24 Le Qiao , Gary W. Slater

Polymer translocation in three dimensions out of planar confinements is studied in this paper. Three membranes are located at $z=-h$, $z=0$ and $z=h_1$. These membranes are impenetrable, except for the middle one at $z=0$, which has a…

Soft Condensed Matter · Physics 2008-01-29 Debabrata Panja , Gerard T. Barkema , Robin C. Ball
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