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Arrays of H-shape microfluidic channels connecting two different fluidic reservoirs have been built with silicon/SU8 microfabrication technologies utilized in production of thermal inkjet printheads. The fluids are delivered to the channels…
Application of computation in many fields are growing fast in last two decades. Increasing on computation performance helps researchers to understand natural phenomena in many fields of science and technology including in life sciences.…
Separation is a crucial step in the analysis of living microparticles. In particular, the selective microseparation of phytoplankton by size and shape remains an open problem, even though these criteria are essential for their gender and/or…
High-resolution blood flow simulations have potential for developing better understanding biophysical phenomena at the microscale, such as vasodilation, vasoconstriction and overall vascular resistance. To this end, we present a scalable…
Syringe pumps are widely used biomedical equipment which offer low-cost solutions to drive and control flow through microfluidic chips. However, they have been shown to transmit mechanical oscillations resulting from their stepper motors,…
We present a novel microfluidic method to produce quasi-monodisperse bubbles with diameters from tens to very few microns. A gaseous rivulet flows over the shallow groove printed on a T-junction exit channel. The triple contact line…
The development of microfluidic devices is still hindered by the lack of robust fundamental building blocks that constitute any fluidic system. An attractive approach is optical actuation because light field interaction is contactless and…
In situ observation of precipitation or phase separation induced by solvent addition is important in studying its dynamics. Combined with optical and fluorescence microscopy, microfluidic devices have been leveraged in studying the phase…
Blood cell classification and counting are vital for the diagnosis of various blood-related diseases, such as anemia, leukemia, and thrombocytopenia. The manual process of blood cell classification and counting is time-consuming, prone to…
Red Blood Cells flowing in a microchannel undergo dispersion in the flow direction due to the non-uniform velocity profile while transverse migration due to cell-wall interactions tends to focus them along the center line. This results in a…
Motivated by the complex rheological behaviors observed in small/micro scale blood vessels, such as the Fahraeus effect, plasma-skimming, shear-thinning, etc., we develop a non-linear suspension model for blood. The viscosity is assumed to…
Segmentation of cerebral blood vessels from Magnetic Resonance Imaging (MRI) is an open problem that could be solved with deep learning (DL). However, annotated data for training is often scarce. Due to the absence of open-source tools, we…
Micro and nanoscale particles are crucial in various fields, from biomedical imaging to environmental processes. While conventional spectroscopy and microscopy methods for characterizing these particles often involve bulky equipment and…
Ferrofluids kept in place by permanent magnet quadrupoles can act as liquid walls to surround a second non-magnetic inside, resulting in a liquid fluidic channel with diameter size ranging from mm down to less than 10 micrometer. Micro…
Of concern in the paper is a study of steady incompressible viscoelastic and electrically conducting fluid flow and heat transfer in a parallel plate channel with stretching walls in the presence of a magnetic field applied externally. The…
Sabeth Verpoorte is professor at the University of Groningen. In this contribution she describes the development of a microfluidic incubation system for drug metabolism studies using a "top-down" precision-cut tissue slice model. She also…
Ultrasound localization microscopy offers new radiation-free diagnostic tools for vascular imaging deep within the tissue. Sequential localization of echoes returned from inert microbubbles with low-concentration within the bloodstream…
We present a microfluidic device that enables trapping, analysis, and on-demand release of individual microparticles through membrane deformation driven by pneumatic actuation. Inspired by Pachinko-style architectures, the system features…
Blood clots, consisting of red blood cells (RBCs) entrapped within a fibrin network, can cause life-threatening conditions such as stroke and heart attack. The recently developed milli-spinner thrombectomy device presents a promising…
Red blood cells (RBCs) are an essential component of blood. A method to include the particulate nature of blood is introduced here with the goal of studying circulation in large-scale realistic vessels. The method uses a combination of the…