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Related papers: Efficiency of molecular motors at maximum power

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The dynamics of molecular motors which occasionally detach from a heterogeneous track like DNA or RNA is considered. Motivated by recent single molecule experiments, we study a simple model for a motor moving along a disordered track using…

Statistical Mechanics · Physics 2009-11-10 Yariv Kafri , David K. Lubensky , David R. Nelson

Living systems at the molecular scale are composed of many constituents with strong and heterogeneous interactions, operating far from equilibrium, and subject to strong fluctuations. These conditions pose significant challenges to…

Statistical Mechanics · Physics 2023-04-11 Emma Lathouwers , Joseph N. E. Lucero , David A. Sivak

Brownian particles interacting sequentially with distinct temperatures and driving forces at each stroke have been tackled as a reliable alternative for the construction of engine setups. However they can behave very inefficiently depending…

Statistical Mechanics · Physics 2022-12-28 Iago N. Mamede , Angel L. L. Stable , C. E. Fiore

The motion of molecular motor is essential to the biophysical functioning of living cells. In principle, this motion can be regraded as a multiple chemical states process. In which, the molecular motor can jump between different chemical…

Biological Physics · Physics 2015-05-19 Yunxin Zhang

Many biological molecular motors and machines are driven by chemical reactions that occur in specific catalytic sites. We study whether the arrival of molecules to such an active site can be accelerated by the presence of a nearby inactive…

Statistical Mechanics · Physics 2025-01-06 Hila Katznelson , Saar Rahav

We study motor traffic on Bethe networks subject to hard-core exclusion for both tightly coupled one-state machines and loosely coupled two-state machines that perform work against a constant load. In both cases we find an…

Statistical Mechanics · Physics 2015-06-18 Natalia Golubeva , Alberto Imparato

Most computer simulations of molecular dynamics take place under equilibrium conditions--in a closed, isolated system, or perhaps one held at constant temperature or pressure. Sometimes, extra tensions, shears, or temperature gradients are…

Statistical Mechanics · Physics 2022-05-25 Alex Albaugh , Todd R. Gingrich

We derive upper and lower bounds for the efficiency of an isothermal molecular machine operating at maximum power. The upper bound is reached when the activated state is close to the fueling or reactant state (Eyring-like), while the lower…

Statistical Mechanics · Physics 2012-02-01 Christian Van den Broeck , Niraj Kumar , Katja Lindenberg

We present a theoretical treatment of energy transfer in a molecular motor described in terms of overdamped Brownian motion on a multidimensional tilted periodic potential. The tilt acts as a thermodynamic force driving the system out of…

Soft Condensed Matter · Physics 2013-10-11 K. J. Challis , Michael W. Jack

We propose a simple model for a motor that generates mechanical motion by exploiting an entropic force arising from the topology of the underlying phase space. We show that the generation of mechanical forces in our system is surprisingly…

Statistical Mechanics · Physics 2015-06-15 Natalia Golubeva , Alberto Imparato , Massimiliano Esposito

Energy transfer plays a vital role in many natural and technological processes. In this work, we study the effects of mechanical motion on the excitation transfer through a chain of interacting molecules with application to biological…

Several recent theories address the efficiency of a macroscopic thermodynamic motor at maximum power and question the so-called "Curzon-Ahlborn (CA) efficiency." Considering the entropy exchanges and productions in an n-sources motor, we…

Statistical Mechanics · Physics 2015-06-03 M. Moreau , B. Gaveau , L. S. Schulman

We propose a two-dimensional model for a complete description of the dynamics of molecular motors, including both the processive movement along track filaments and the dissociation from the filaments. The theoretical results on the…

Biomolecules · Quantitative Biology 2009-11-10 Ping Xie , Shuo-Xing Dou , Peng-Ye Wang

Single-molecule experiments have found near-perfect thermodynamic efficiency in the rotary motor F1-ATP synthase. To help elucidate the principles underlying nonequilibrium energetic efficiency in such stochastic machines, we investigate…

Statistical Mechanics · Physics 2019-09-05 Joseph N. E. Lucero , Aliakbar Mehdizadeh , David A. Sivak

A molecular motor is made of either a single macromolecule or a macromolecular complex. Just like their macroscopic counterparts, molecular motors "transduce" input energy into mechanical work. All the nano-motors considered here operate…

Biological Physics · Physics 2013-07-18 Debashish Chowdhury

F$_{1}$-ATPase is a rotary molecular motor that \emph{in vivo} is subject to strong nonequilibrium driving forces. There is great interest in understanding the operational principles governing its high efficiency of free-energy…

Statistical Mechanics · Physics 2022-12-29 Deepak Gupta , Steven J. Large , Shoichi Toyabe , David A. Sivak

Catalysis-driven synthetic molecular motors operate in a loose mechanochemical coupling regime, one in which a decomposition of a fuel molecule does not reliably produce a forward step. In that regime, stochastic backward steps can…

Statistical Mechanics · Physics 2026-01-16 Geyao Gu , Drew Alvarez , John Strahan , Alex Albaugh , Emanuele Penocchio , Todd R. Gingrich

Fueled by the hydrolysis of ATP, the motor protein kinesin literally walks on two legs along the biopolymer microtubule. The number of accidental backsteps that kinesin takes appears to be much larger than what one would expect given the…

Subcellular Processes · Quantitative Biology 2009-11-13 M. Bier , F. J. Cao

As engineering advances toward the nanoscale, understanding design principles for molecular motors becomes increasingly valuable. Many molecular motors consist of coupled components transducing one free-energy source into another. Here, we…

Statistical Mechanics · Physics 2026-02-09 Sara Iranbakhsh , David A. Sivak

A transition rate model of cargo transport by $N$ molecular motors is proposed. Under the assumption of steady state, the force-velocity curve of multi-motor system can be derived from the force-velocity curve of single motor. Our work…

Biological Physics · Physics 2011-11-08 Ziqing Wang , Ming Li