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I did off-lattice 3D Monte Carlo simulations for polymer translocation through a narrow pore at low external field, trying to be as close to a direct approach as possible. The process was found non equilibrium globally, but dynamics of the…

Soft Condensed Matter · Physics 2008-06-18 Stanislav Kotsev

In this work we study the noise induced effects on the dynamics of short polymers crossing a potential barrier, in the presence of a metastable state. An improved version of the Rouse model for a flexible polymer has been adopted to mimic…

Statistical Mechanics · Physics 2009-11-13 N. Pizzolato , A. Fiasconaro , B. Spagnolo

We study the passage times of a translocating polymer of length $N$ in three dimensions, while it is pulled through a narrow pore with a constant force $F$ applied to one end of the polymer. At small to moderate forces, satisfying the…

Soft Condensed Matter · Physics 2008-02-14 Debabrata Panja , Gerard T. Barkema

We study the driven translocation of a semi-flexible polymer through a nanopore by means of a modified version of the iso-flux tension propagation theory (IFTP), and extensive molecular dynamics (MD) simulations. We show that in contrast to…

Soft Condensed Matter · Physics 2016-12-28 Jalal Sarabadani , Timo Ikonen , Harri Mökkönen , Tapio Ala-Nissila , Spencer Carson , Meni Wanunu

DNA translocation through nanopores is one of the most promising strategies for the next-generation sequencing technologies. Most part of experimental and numerical works has focused on polymer translocation biased by electrophoresis, where…

Soft Condensed Matter · Physics 2018-02-07 Timothée Menais

We employ a three-dimensional molecular dynamics to simulate translocation of a polymer through a nanopore driven by an external force. The translocation is investigated for different three pore diameter and two different external forces.…

Computational Physics · Physics 2019-12-03 Mohammadreza Niknam Hamidabad , Rouhollah Haji Abdolvahab

We present event distributions for the polymer translocation obtained by extensive Langevin dynamics simulations. Such distributions have not been reported previously and they provide new understanding of the stochastic characteristics of…

Soft Condensed Matter · Physics 2012-04-13 R. P. Linna , K. Kaski

Dynamics of a discrete polymer in time-dependent external potentials is studied with the master equation approach. We consider both stochastic and deterministic switching mechanisms for the potential states and give the essential equations…

Statistical Mechanics · Physics 2008-06-25 Janne Kauttonen , Juha Merikoski , Otto Pulkkinen

We study translocation of semiflexible polymers driven by force $f_d$ inside a nanometer-scale pore using our three-dimensional Langevin dynamics model. We show that the translocation time $\tau$ increases with increasing bending rigidity…

Biological Physics · Physics 2018-06-27 Pauli M. Suhonen , Riku P. Linna

In this work we study the assisted translocation of a polymer across a membrane nanopore, inside which a molecular motor exerts a force fuelled by the hydrolysis of ATP molecules. In our model the motor switches to its active state for a…

Soft Condensed Matter · Physics 2018-03-26 A. Fiasconaro , J. J. Mazo , F. Falo

One of the most fundamental quantities associated with polymer translocation through a nanopore is the translocation time $\tau$ and its dependence on the chain length $N$. Our simulation results based on both the bond fluctuation Monte…

Soft Condensed Matter · Physics 2008-11-08 Kaifu Luo , Tapio Ala-Nissila , See-Chen Ying , Pawel Pomorski , Mikko Karttunen

In this paper we study the unfolding transition observed in polymer stretching experiments. We use a known model and extend it with a mean-field-like interaction. Expressions for all necessary thermodynamic variables as a function of the…

Statistical Mechanics · Physics 2007-05-23 Erik Van der Straeten , Jan Naudts

We present scaling estimates for characteristic times $\tau_{\rm lin}$ and $\tau_{\rm br}$ of pulling ideal linear and randomly branched polymers of $N$ monomers into a small hole by a force $f$. We show that the absorbtion process develops…

Statistical Mechanics · Physics 2009-11-11 A. Y. Grosberg , S. Nechaev , M. Tamm , O. Vasilyev

We investigate by Monte Carlo simulations the zipping and unzipping dynamics of two polymers connected by one end and subject to an attractive interaction between complementary monomers. In zipping, the polymers are quenched from a high…

Soft Condensed Matter · Physics 2011-02-15 Alessandro Ferrantini , Enrico Carlon

We revisit the Fokker-Planck based theory of driven polymer translocation through a narrow nanopore. A bead-spring model of a uniformly charged polyelectrolyte chain translocating through a semi-implicit model of a nanopore embedded in a…

Soft Condensed Matter · Physics 2025-12-02 Bhavesh R. Sarode , Harshwardhan H. Katkar

We derive a general mean-field theory of inhomogeneous polymer dynamics; a theory whose form has been speculated and widely applied, but not heretofore derived. Our approach involves a functional integral representation of a…

Soft Condensed Matter · Physics 2015-06-18 Glenn H. Fredrickson , Henri Orland

We study the translocation of a semiflexible polymer through a conical channel with attractive surface interactions and a driving force which varies spatially inside the channel. Using the results of the translocation dynamics of a flexible…

Soft Condensed Matter · Physics 2022-11-15 Andri Sharma , Rajeev Kapri , Abhishek Chaudhuri

The translocation dynamics of a polymer chain through a nanopore in the absence of an external driving force is analyzed by means of scaling arguments, fractional calculus, and computer simulations. The problem at hand is mapped on a one…

Soft Condensed Matter · Physics 2007-07-29 J. L. A. Dubbeldam , A. Milchev , V. G. Rostiashvili , T. A. Vilgis

The translocation of a polymer through a pore in a membrane separating fluids of different viscosities is studied via several computational approaches. Starting with the polymer halfway, we find that as a viscosity difference across the…

Soft Condensed Matter · Physics 2013-04-17 Hendrick W. de Haan , Gary W. Slater

The theoretical formulation of driven polymer translocation through nanopores is complicated by the combination of the pore electrohydrodynamics and the nonequilibrium polymer dynamics originating from the conformational polymer…

Soft Condensed Matter · Physics 2019-01-15 Sahin Buyukdagli , Jalal Sarabadani , Tapio Ala-Nissila