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A normal network is uniquely determined by the set of phylogenetic trees that it displays. Given a set $\mathcal{P}$ of rooted binary phylogenetic trees, this paper presents a polynomial-time algorithm that reconstructs the unique binary…

Combinatorics · Mathematics 2024-07-10 Magnus Bordewich , Simone Linz , Charles Semple

Phylogenetic networks provide a way to describe and visualize evolutionary histories that have undergone so-called reticulate evolutionary events such as recombination, hybridization or horizontal gene transfer. The level k of a network…

Populations and Evolution · Quantitative Biology 2008-07-21 Leo van Iersel , Steven Kelk , Matthias Mnich

Phylogenetic trees and networks are graphs used to model evolutionary relationships, with trees representing strictly branching histories and networks allowing for events in which lineages merge, called reticulation events. While the…

Populations and Evolution · Quantitative Biology 2026-04-17 Martin Frohn , Niels Holtgrefe , Leo van Iersel , Mark Jones , Steven Kelk

Invariants for complicated objects such as those arising in phylogenetics, whether they are invariants as matrices, polynomials, or other mathematical structures, are important tools for distinguishing and working with such objects. In this…

Populations and Evolution · Quantitative Biology 2022-04-06 Joan Carles Pons , Tomás M. Coronado , Michael Hendriksen , Andrew Francis

Galled trees, directed acyclic graphs that model evolutionary histories with isolated hybridization events, have become very popular due to both their biological significance and the existence of polynomial time algorithms for their…

Populations and Evolution · Quantitative Biology 2009-06-08 Gabriel Cardona , Merce Llabres , Francesc Rossello , Gabriel Valiente

We propose a statistical method to test whether two phylogenetic trees with given alignments are significantly incongruent. Our method compares the two distributions of phylogenetic trees given by the input alignments, instead of comparing…

Populations and Evolution · Quantitative Biology 2010-04-14 Elissaveta Arnaoudova , David Haws , Peter Huggins , Jerzy W. Jaromczyk , Neil Moore , Chris Schardl , Ruriko Yoshida

Phylogenetic networks are a generalization of evolutionary or phylogenetic trees that are commonly used to represent the evolution of species which cross with one another. A special type of phylogenetic network is an {\em $X$-cactus}, which…

Populations and Evolution · Quantitative Biology 2021-09-08 Andrew Francis , Katharina T. Huber , Vincent Moulton , Taoyang Wu

An evolutionary tree is a cascade of bifurcations starting from a single common root, generating a growing set of daughter species as time goes by. Species here is a general denomination for biological species, spoken languages or any other…

Quantitative Methods · Quantitative Biology 2013-08-26 Paulo Murilo Castro de Oliveira

We present the first fixed-parameter algorithm for constructing a tree-child phylogenetic network that displays an arbitrary number of binary input trees and has the minimum number of reticulations among all such networks. The algorithm…

Discrete Mathematics · Computer Science 2019-07-22 Leo van Iersel , Remie Janssen , Mark Jones , Yukihiro Murakami , Norbert Zeh

In this paper, we lay the groundwork on the comparison of phylogenetic networks based on edge contractions and expansions as edit operations, as originally proposed by Robinson and Foulds to compare trees. We prove that these operations…

Data Structures and Algorithms · Computer Science 2025-02-21 Bertrand Marchand , Nadia Tahiri , Olivier Tremblay-Savard , Manuel Lafond

Phylogenetic networks generalize phylogenetic trees by representing reticulate evolution. Tree-based networks and their support trees have been extensively studied, but not all networks are tree-based. To measure how far such networks are…

Populations and Evolution · Quantitative Biology 2026-05-27 Takatora Suzuki

A wide range of applications and research has been done with genome-scale metabolic models. In this work we describe a methodology for comparing metabolic networks constructed from genome-scale metabolic models and how to apply this…

Molecular Networks · Quantitative Biology 2026-02-06 D. Gamermann , A. Montagud , J. A. Conejero , P. F. de Córdoba , J. F. Urchieguía

Understanding the evolution of a set of genes or species is a fundamental problem in evolutionary biology. The problem we study here takes as input a set of trees describing {possibly discordant} evolutionary scenarios for a given set of…

Data Structures and Algorithms · Computer Science 2019-07-10 Cedric Chauve , Mark Jones , Manuel Lafond , Céline Scornavacca , Mathias Weller

Phylogenetic networks are graphs that are used to represent evolutionary relationships between different taxa. They generalize phylogenetic trees since for example, unlike trees, they permit lineages to combine. Recently, there has been…

Populations and Evolution · Quantitative Biology 2025-08-05 Katharina T. Huber , Leo van Iersel , Mark Jones , Vincent Moulton , Leonie Veenema - Nipius

Phylogenetic networks are an important way to represent evolutionary histories that involve reticulations such as hybridization or horizontal gene transfer, yet fundamental questions such as how many networks there are that satisfy certain…

Populations and Evolution · Quantitative Biology 2025-02-21 Andrew Francis , Michael Hendriksen

Polyploidization is an evolutionary process by which a species acquires multiple copies of its complete set of chromosomes. The reticulate nature of the signal left behind by it means that phylogenetic networks offer themselves as a…

Populations and Evolution · Quantitative Biology 2023-02-21 Katharina T. Huber , Liam J. Maher

In evolutionary biology, networks are becoming increasingly used to represent evolutionary histories for species that have undergone non-treelike or reticulate evolution. Such networks are essentially directed acyclic graphs with a leaf set…

Populations and Evolution · Quantitative Biology 2023-08-23 Katharina T. Huber , Leo van Iersel , Vincent Moulton , Guillaume Scholz

Phylogenomics commonly aims to construct evolutionary trees from genomic sequence information. One way to approach this problem is to first estimate event-labeled gene trees (i.e., rooted trees whose non-leaf vertices are labeled by…

Combinatorics · Mathematics 2019-05-09 Marc Hellmuth , Katharina T. Huber , Vincent Moulton

In this article we study the treewidth of the \emph{display graph}, an auxiliary graph structure obtained from the fusion of phylogenetic (i.e., evolutionary) trees at their leaves. Earlier work has shown that the treewidth of the display…

Discrete Mathematics · Computer Science 2017-04-03 Steven Kelk , Georgios Stamoulis , Taoyang Wu

Phylogenetic networks are directed acyclic graphs that depict the genomic evolution of related taxa. Reticulation nodes in such networks (nodes with more than one parent) represent reticulate evolutionary events, such as recombination,…

Populations and Evolution · Quantitative Biology 2024-11-21 Alexey Markin , Sriram Vijendran , Oliver Eulenstein
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