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In this paper, we study an adaptive spatial network. We consider an SIS (susceptible-infectedsusceptible) epidemic on the network, with a link/contact rewiring process constrained by spatial proximity. In particular, we assume that…

Populations and Evolution · Quantitative Biology 2016-11-25 P. Rattana , L. Berthouze , I. Z. Kiss

We investigate the folding behavior of protein sequences by numerically studying all sequences with maximally compact lattice model through exhaustive enumeration. We get the prion-like behavior of protein folding. Individual proteins…

Biomolecules · Quantitative Biology 2014-11-18 Yong-Yun Ji , You-Quan Li , Jun-Wen Mao , Xiao-Wei Tang

Certain biochemical reactions can only be triggered after binding of a sufficient number of particles to a specific target region such as an enzyme or a protein sensor. We investigate the distribution of the reaction time, i.e., the first…

Chemical Physics · Physics 2022-10-10 Denis S. Grebenkov , Aanjaneya Kumar

Understanding of how protein interaction networks (PIN) of living organisms have evolved or are organized can be the first stepping stone in unveiling how life works on a fundamental ground. Here we introduce a hybrid network model composed…

Molecular Networks · Quantitative Biology 2007-05-23 K. -I. Goh , B. Kahng , D. Kim

Transport of rodlike particles in confinement environments of macromolecular networks plays crucial roles in many important biological processes and technological applications. The relevant understanding has been limited to thin rods with…

The reorientation dynamics of local tangent vectors of chains in isotropic amorphous melts containing semiflexible model polymers was studied by molecular dynamics simulations. The reorientation is strongly influenced both by the local…

Soft Condensed Matter · Physics 2016-08-15 Roland Faller , Florian Müller-Plathe , Andreas Heuer

In many complex systems, the dynamic processes that take place on a network and the changes in the network topology are intertwined. Here, we propose a model of coevolutionary dynamics of information spreading which is accompanied with link…

Physics and Society · Physics 2023-11-01 Jeehye Choi , Byungjoon Min

We present simulation results for the contact process on regular, cubic networks that are composed of a one-dimensional lattice and a set of long edges with unbounded length. Networks with different sets of long edges are considered, that…

Statistical Mechanics · Physics 2015-05-13 R. Juhász , G. Ódor

Epidemic containment is a major concern when confronting large-scale infections in complex networks. Many works have been devoted to analytically understand how to restructure the network to minimize the impact of major outbreaks of…

Physics and Society · Physics 2018-12-27 Joan T. Matamalas , Alex Arenas , Sergio Gómez

Finding out statistically significant words in DNA and protein sequences forms the basis for many genetic studies. By applying the maximal entropy principle, we give one systematic way to study the nonrandom occurrence of words in DNA or…

Biological Physics · Physics 2009-11-06 Rui Hu , Bin Wang

We derive an analytic expression for site-specific stationary distributions of amino acids from the Structurally Constrained Neutral (SCN) model of protein evolution with conservation of folding stability. The stationary distributions that…

Biomolecules · Quantitative Biology 2007-05-23 Markus Porto , H. Eduardo Roman , Michele Vendruscolo , Ugo Bastolla

The dynamical characterization of proteins is crucial to understand protein function. From a microscopic point of view, protein dynamics is governed by the local atomic interactions that, in turn, trigger the functional conformational…

Biomolecules · Quantitative Biology 2010-01-21 Francesco Rao

Random Threshold Networks with sparse, asymmetric connections show complex dynamical behavior similar to Random Boolean Networks, with a transition from ordered to chaotic dynamics at a critical average connectivity $K_c$. In this type of…

Statistical Mechanics · Physics 2009-11-07 Thimo Rohlf , Stefan Bornholdt

Genes are connected in regulatory networks, often modelled by ordinary differential equations. Changes in expression of a gene propagate to other genes along paths in the network. At a stable state, the system's Jacobian matrix confers…

Molecular Networks · Quantitative Biology 2014-11-03 Arne B. Gjuvsland , Erik Plahte

The complexity of the cells can be described and understood by a number of networks such as protein-protein interaction, cytoskeletal, organelle, signalling, gene transcription and metabolic networks. All these networks are highly dynamic…

Molecular Networks · Quantitative Biology 2007-07-26 Mate S. Szalay , Istvan A. Kovacs , Tamas Korcsmaros , Csaba Bode , Peter Csermely

There is a rich history of models for the interaction of a biological contagion like influenza with the spread of related information such as an influenza vaccination campaign. Recent work on the spread of interacting contagions on networks…

Physics and Society · Physics 2020-09-02 Laurent Hébert-Dufresne , Dina Mistry , Benjamin M. Althouse

We study numerically the variability of the outbreak of diseases on complex networks. We use a SI model to simulate the disease spreading at short times, in homogeneous and in scale-free networks. In both cases, we study the effect of…

Statistical Mechanics · Physics 2007-05-23 Pascal Crépey , Fabián P. Alvarez , Marc Barthélemy

Self-avoiding random walks were performed on protein residue networks. Compared with protein residue networks with randomized links, the probability of a walk being successful is lower and the length of successful walks shorter in…

Molecular Networks · Quantitative Biology 2013-06-11 Susan Khor

We study the effect of the connectivity pattern of complex networks on the propagation dynamics of epidemics. The growth time scale of outbreaks is inversely proportional to the network degree fluctuations, signaling that epidemics spread…

Disordered Systems and Neural Networks · Physics 2009-11-10 Marc Barthelemy , Alain Barrat , Romualdo Pastor-Satorras , Alessandro Vespignani

When nodes can repeatedly update their behavior (as in agent-based models from computational social science or repeated-game play settings) the problem of optimal network seeding becomes very complex. For a popular spreading-phenomena model…

Social and Information Networks · Computer Science 2023-06-22 Gwen Spencer