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Enzyme-based systems have been shown to undergo directional motion in response to their substrate gradient. Here, we formulate a kinetic model to analyze the directional movement of an ensemble of protein molecules in response to a gradient…

Biological Physics · Physics 2021-03-26 Niladri Sekhar Mandal , Ayusman Sen

We analyse the stability of linear dynamical systems defined on sparse, random graphs with predator-prey, competitive, and mutualistic interactions. These systems are aimed at modelling the stability of fixed points in large systems defined…

Statistical Mechanics · Physics 2025-01-30 Andrea Marcello Mambuca , Chiara Cammarota , Izaak Neri

The rapid diffusion of information and the adoption of social behaviors are of critical importance in situations as diverse as collective actions, pandemic prevention, or advertising and marketing. Although the dynamics of large cascades…

Physics and Society · Physics 2020-12-30 Hao Peng , Azadeh Nematzadeh , Daniel M. Romero , Emilio Ferrara

The determination of protein functions is one of the most challenging problems of the post-genomic era. The sequencing of entire genomes and the possibility to access gene's co-expression patterns has moved the attention from the study of…

Statistical Mechanics · Physics 2007-05-23 A. Vazquez , A. Flammini , A. Maritan , A. Vespignani

Spreading phenomena on networks are essential for the collective dynamics of various natural and technological systems, from information spreading in gene regulatory networks to neural circuits or from epidemics to supply networks…

Physics and Society · Physics 2021-06-01 Justine Wolter , Benedict Lünsmann , Xiaozhu Zhang , Malte Schröder , Marc Timme

Transcription factor binding sites vary in their specificity, both within and between species. Binding specificity has a strong impact on the evolution of gene expression, because it determines how easily regulatory interactions are gained…

Populations and Evolution · Quantitative Biology 2013-12-30 Alexander J. Stewart , Joshua B. Plotkin

Recently much attention has been paid to the study of the robustness of interdependent and multiplex networks and, in particular, networks of networks. The robustness of interdependent networks can be evaluated by the size of a mutually…

Statistical Mechanics · Physics 2015-06-18 Ginestra Bianconi , Sergey N. Dorogovtsev

Many real networks present a bounded scale-free behavior with a connectivity cut-off due to physical constraints or a finite network size. We study epidemic dynamics in bounded scale-free networks with soft and hard connectivity cut-offs.…

Statistical Mechanics · Physics 2009-11-07 Romualdo Pastor-Satorras , Alessandro Vespignani

Self-organization of robust and efficient networks is important for a future design of communication or transportation systems, because both characteristics are not coexisting in many real networks. As one of the candidates for the…

Physics and Society · Physics 2022-06-15 Fuxuan Liao , Yukio Hayashi

Mutational robustness is the extent to which an organism has evolved to withstand the effects of deleterious mutations. We explored the extent of mutational robustness in the budding yeast by genome wide dosage suppressor analysis of 53…

We study numerically the dynamics of a network of all-to-all-coupled, identical sub-networks consisting of diffusively coupled, non-identical FitzHugh--Nagumo oscillators. For a large range of within- and between-network couplings, the…

Chaotic Dynamics · Physics 2018-10-17 Leonardo Rydin Gorjão , Arindam Saha , Gerrit Ansmann , Ulrike Feudel , Klaus Lehnertz

The spreading of epidemics is very much determined by the structure of the contact network, which may be impacted by the mobility dynamics of the individuals themselves. In confined scenarios where a small, closed population spends most of…

Physics and Society · Physics 2018-05-09 Clara Granell , Peter J. Mucha

Proximity networks are time-varying graphs representing the closeness among humans moving in a physical space. Their properties have been extensively studied in the past decade as they critically affect the behavior of spreading phenomena…

Physics and Society · Physics 2019-11-28 Fragkiskos Papadopoulos , Marco Antonio Rodríguez Flores

We consider multiple diseases spreading in a static Configuration Model network. We make standard assumptions that infection transmits from neighbor to neighbor at a disease-specific rate and infected individuals recover at a…

Populations and Evolution · Quantitative Biology 2015-06-11 Joel C. Miller

Global transposable characteristics in the complete DNA sequence of the Saccharomyces cevevisiae yeast is determined by using the metric representation and recurrence plot methods. In the form of the correlation distance of nucleotide…

Genomics · Quantitative Biology 2015-06-03 Zuo-Bing Wu

We propose a model for the transmission of perturbations across the amino acids of a protein represented as an interaction network. The dynamics consists of a Susceptible-Infected (SI) model based on the Caputo fractional-order derivative.…

Molecular Networks · Quantitative Biology 2020-07-01 Luciano Abadias , Gissell Estrada-Rodriguez , Ernesto Estrada

We analyze a model of interacting agents (e.g. prebiotic chemical species) which are represended by nodes of a network, whereas their interactions are mapped onto directed links between these nodes. On a fast time scale, each agent follows…

Populations and Evolution · Quantitative Biology 2009-11-13 Adrian M. Seufert , Frank Schweitzer

The control of complex networks is of paramount importance in areas as diverse as ecosystem management, emergency response, and cell reprogramming. A fundamental property of networks is that perturbations to one node can affect other nodes,…

Disordered Systems and Neural Networks · Physics 2013-07-15 Sean P. Cornelius , William L. Kath , Adilson E. Motter

The diffusion-controlled limit of reaction times for site-specific DNA-binding proteins is derived from first principles. We follow the generally accepted concept that a protein propagates via two competitive modes, a three-dimensional…

Biological Physics · Physics 2009-11-11 Konstantin V. Klenin , Holger Merlitz , Joerg Langowski , Chen-Xu Wu

Convergence of resource allocation algorithms is well covered in the literature as convergence to a steady state is important due to stability and performance. However, research is lacking when it comes to the propagation of change that…

Information Theory · Computer Science 2012-10-19 Brage Ellingsæter , Torleiv Maseng
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