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Entropy and information provide natural measures of correlation among elements in a network. We construct here the information theoretic analog of connected correlation functions: irreducible $N$--point correlation is measured by a decrease…

Biological Physics · Physics 2016-09-08 Elad Schneidman , Susanne Still , Michael J. Berry , William Bialek

Boolean networks are discrete dynamical systems in which the state (zero or one) of each node is updated at each time t to a state determined by the states at time t-1 of those nodes that have links to it. When these systems are used to…

Molecular Networks · Quantitative Biology 2012-02-28 Andrew Pomerance , Michelle Girvan , Ed Ott

One of the fundamental steps toward understanding a complex system is identifying variation at the scale of the system's components that is most relevant to behavior on a macroscopic scale. Mutual information provides a natural means of…

Machine Learning · Computer Science 2024-03-20 Kieran A. Murphy , Dani S. Bassett

In this paper, we present an analytical framework to derive the performance of a molecular communication system where a transmitter bio-nano-machine (TBN) is communicating with a fully-absorbing spherical receiver bio-nano-machine (RBN) in…

Information Theory · Computer Science 2020-04-07 Nithin V. Sabu , Abhishek K. Gupta

Recurrent neural networks (RNNs) are complex dynamical systems, capable of ongoing activity without any driving input. The long-term behavior of free-running RNNs, described by periodic, chaotic and fixed point attractors, is controlled by…

Neurons and Cognition · Quantitative Biology 2021-08-06 Claus Metzner , Patrick Krauss

Boolean networks are a valuable class of discrete dynamical systems models, but they remain fundamentally limited by their inability to capture multi-way interactions in their components. To remedy this limitation, we propose a model of…

Dynamical Systems · Mathematics 2024-09-02 Kevin M. Stoltz , Cliff A. Joslyn

Correlations disguised in various forms underlie a host of important phenomena in classical and quantum systems, such as information and energy exchanges. The quantum mutual information and the norm of the correlation matrix are both…

Quantum Physics · Physics 2020-04-15 S. Alipour , S. Tuohino , A. T. Rezakhani , T. Ala-Nissila

Regulatory networks (RNs) are a well-accepted modelling formalism in computational systems biology. The control of RNs is currently receiving a lot of attention because it provides a computational basis for cell reprogramming -- an…

Systems and Control · Electrical Eng. & Systems 2022-03-01 Luboš Brim , Samuel Pastva , David Šafránek , Eva Šmijáková

Our daily social and political life is more and more impacted by social networks. The functioning of our living bodies is deeply dependent on biological regulation networks such as neural, genetic, and protein networks. And the physical…

Discrete Mathematics · Computer Science 2022-04-25 Jacques Demongeot , Tarek Melliti , Mathilde Noual , Damien Regnault , Sylvain Sené

A Boolean network (BN) with $n$ components is a discrete dynamical system described by the successive iterations of a function $f:\{0,1\}^n \to \{0,1\}^n$. This model finds applications in biology, where fixed points play a central role.…

Combinatorics · Mathematics 2022-02-10 Florian Bridoux , Amélia Durbec , Kévin Perrot , Adrien Richard

Genetic regulatory networks (GRNs) have been widely studied, yet there is a lack of understanding with regards to the final size and properties of these networks, mainly due to no network currently being complete. In this study, we analyzed…

Molecular Networks · Quantitative Biology 2019-03-13 Adrian I. Campos-González , Julio A. Freyre-González

Learning a Bayesian network is an NP-hard problem and with an increase in the number of nodes, classical algorithms for learning the structure of Bayesian networks become inefficient. In recent years, some methods and algorithms for…

Machine Learning · Computer Science 2022-08-23 Yury Kaminsky , Irina Deeva

Estimating the influence that individual nodes have on one another in a Boolean network is essential to predict and control the system's dynamical behavior, for example, detecting key therapeutic targets to control pathways in models of…

Physics and Society · Physics 2023-11-02 Thomas Parmer , Filippo Radicchi

As a discrete approach to genetic regulatory networks, Boolean models provide an essential qualitative description of the structure of interactions among genes and proteins. Boolean models generally assume only two possible states…

Molecular Networks · Quantitative Biology 2007-05-23 Madalena Chaves , Eduardo D. Sontag , Reka Albert

Boolean networks have been the object of much attention, especially since S. Kauffman proposed them in the 1960's as models for gene regulatory networks. These systems are characterized by being defined on a Boolean state space and by…

Molecular Networks · Quantitative Biology 2008-01-30 Winfried Just , German Enciso

One of the characteristic features of genetic networks is their inherent robustness, that is, their ability to retain functionality in spite of the introduction of random errors. In this paper, we seek to better understand how robustness is…

Molecular Networks · Quantitative Biology 2009-04-29 Arnab Bhattacharyya , Bernhard Haeupler

We study the capacity with which a system of independent neuron-like units represents a given set of stimuli. We assume that each neuron provides a fixed amount of information, and that the information provided by different neurons has a…

Disordered Systems and Neural Networks · Physics 2007-05-23 Ines Samengo

The Internet is a complex network of interconnected routers and the existence of collective behavior such as congestion suggests that the correlations between different connections play a crucial role. It is thus critical to measure and…

Disordered Systems and Neural Networks · Physics 2009-11-07 Marc Barthelemy , Bernard Gondran , Eric Guichard

Mutual Information (MI) is a powerful statistical measure that quantifies shared information between random variables, particularly valuable in high-dimensional data analysis across fields like genomics, natural language processing, and…

Machine Learning · Computer Science 2024-12-02 Andre O. Falcao

Sequence models assign probabilities to variable-length sequences such as natural language texts. The ability of sequence models to capture temporal dependence can be characterized by the temporal scaling of correlation and mutual…

Machine Learning · Computer Science 2019-05-13 Huitao Shen
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