English

The Stability of Boolean Networks with Generalized Canalizing Rules

Molecular Networks 2012-02-28 v3

Abstract

Boolean networks are discrete dynamical systems in which the state (zero or one) of each node is updated at each time t to a state determined by the states at time t-1 of those nodes that have links to it. When these systems are used to model genetic control, the case of 'canalizing' update rules is of particular interest. A canalizing rule is one for which a node state at time tt is determined by the state at time t-1 of a single one of its inputs when that inputting node is in its canalizing state. Previous work on the order/disorder transition in Boolean networks considered complex, non-random network topology. In the current paper we extend this previous work to account for canalizing behavior.

Keywords

Cite

@article{arxiv.0910.0509,
  title  = {The Stability of Boolean Networks with Generalized Canalizing Rules},
  author = {Andrew Pomerance and Michelle Girvan and Ed Ott},
  journal= {arXiv preprint arXiv:0910.0509},
  year   = {2012}
}

Comments

20 pages, 3 figures

R2 v1 2026-06-21T13:53:39.762Z