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The regulation of the cell state is a complex process involving several components. These complex dynamics can be modeled using Boolean networks, allowing us to explain the existence of different cell states and the transition between them.…

Molecular Networks · Quantitative Biology 2010-01-28 Elke K. Markert , Nils Baas , Arnold J. Levine , Alexei Vazquez

Boolean networks have been widely used in many areas of science and engineering to represent various dynamical behaviour. In systems biology, they became useful tools to study the dynamical characteristics of large-scale biomolecular…

Dynamical Systems · Mathematics 2024-01-01 Jongrae Kim , Woojeong Lee , Kwang-Hyun Cho

Mutualistic networks are used to study the structure and processes inherent to mutualistic relationships. In this paper, we introduce a random matrix ensemble (RME) representing the adjacency matrices of mutualistic networks composed by two…

Disordered Systems and Neural Networks · Physics 2021-11-10 C. T. Martínez-Martínez , J. A. Méndez-Bermúdez , Thomas Peron , Yamir Moreno

While information processing in complex systems can be described in abstract, general terms, there are cases in which the relation between these computations and the physical substrate of the underlying system is itself of interest.…

Neurons and Cognition · Quantitative Biology 2017-08-16 Pedro A. M. Mediano , Murray Shanahan

This paper proposes a distributed algorithm for average consensus in a multi-agent system under a fixed bidirectional communication topology, in the presence of malicious agents (nodes) that may try to influence the average consensus…

Multiagent Systems · Computer Science 2023-09-06 Christoforos N. Hadjicostis , Alejandro D. Dominguez-Garcia

Realistic networks display not only a complex topological structure, but also a heterogeneous distribution of weights in the connection strengths. Here we study synchronization in weighted complex networks and show that the…

Disordered Systems and Neural Networks · Physics 2007-05-23 Changsong Zhou , Adilson E. Motter , Jurgen Kurths

Changes in a cell's external or internal conditions are usually reflected in the concentrations of the relevant transcription factors. These proteins in turn modulate the expression levels of the genes under their control and sometimes need…

Molecular Networks · Quantitative Biology 2013-08-01 Gasper Tkacik , Curtis G Callan , William Bialek

Canalization is a key organizing principle in complex systems, particularly in gene regulatory networks. It describes how certain input variables exert dominant control over a function's output, thereby imposing hierarchical structure and…

Discrete Mathematics · Computer Science 2025-10-31 Claus Kadelka

Cells sense environmental signals and transmit information intracellularly through changes in the abundance of molecular components. Such molecular abundances can be measured in single cells and exhibit significant heterogeneity in clonal…

Quantitative Methods · Quantitative Biology 2024-09-27 Raymond Fan , Andreas Hilfinger

Multielectrode arrays allow recording of the activity of many single neurons, from which correlations can be calculated. The functional roles of correlations can be revealed by the measures of the information conveyed by neuronal activity;…

Statistical Mechanics · Physics 2009-09-25 Michele Bezzi , Mathew E. Diamond , Alessandro Treves

We observe deterministic chaos in a simple network of electronic logic gates that are not regulated by a clocking signal. The resulting power spectrum is ultra-wide-band, extending from dc to beyond 2 GHz. The observed behavior is…

The information bottleneck (IB) principle has been suggested as a way to analyze deep neural networks. The learning dynamics are studied by inspecting the mutual information (MI) between the hidden layers and the input and output. Notably,…

Machine Learning · Computer Science 2022-02-15 Stephan Sloth Lorenzen , Christian Igel , Mads Nielsen

We correct claims about lower bounds on mutual information (MI) between real-valued random variables made in A. Kraskov {\it et al.}, Phys. Rev. E {\bf 69}, 066138 (2004). We show that non-trivial lower bounds on MI in terms of linear…

Data Analysis, Statistics and Probability · Physics 2013-05-29 David V. Foster , Peter Grassberger

Complex systems are characterized by multiple spatial and temporal scales. A natural framework to capture their multiscale nature is that of multilayer networks, where different layers represent distinct physical processes that often…

Statistical Mechanics · Physics 2024-04-29 Giorgio Nicoletti , Daniel Maria Busiello

This review explains in a self-contained way the properties of random Boolean networks and their attractors, with a special focus on critical networks. Using small example networks, analytical calculations, phenomenological arguments, and…

Statistical Mechanics · Physics 2008-11-14 Barbara Drossel

A method to estimate the time-dependent correlation via an empirical bias estimate of the time-delayed mutual information for a time-series is proposed. In particular, the bias of the time-delayed mutual information is shown to often be…

Chaotic Dynamics · Physics 2016-01-20 DJ Albers , George Hripcsak

The complicated interactions in presence of disorder lead to a correlated randomization of states. The Hamiltonian as a result behaves like a multi-parametric random matrix with correlated elements. We show that the eigenvalue correlations…

Disordered Systems and Neural Networks · Physics 2009-11-10 Pragya Shukla

This article is set in the field of regulation networks modeled by discrete dynamical systems. It focuses on Boolean automata networks. In such networks, there are many ways to update the states of every element. When this is done…

Discrete Mathematics · Computer Science 2015-03-19 Mathilde Noual

Real-world systems are characterized by complex interactions of their internal degrees of freedom, while living in ever-changing environments whose net effect is to act as additional couplings. Here, we introduce a paradigmatic interacting…

Statistical Mechanics · Physics 2021-11-23 Giorgio Nicoletti , Daniel Maria Busiello

For a large multi-hop wireless network, nodes are preferable to make distributed and localized link-scheduling decisions with only interactions among a small number of neighbors. However, for a slowly decaying channel and densely populated…

Machine Learning · Computer Science 2012-03-06 Sung-eok Jeon , Chuanyi Ji
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