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The theory of monotone dynamical systems has been found very useful in the modeling of some gene, protein, and signaling networks. In monotone systems, every net feedback loop is positive. On the other hand, negative feedback loops are…

Dynamical Systems · Mathematics 2009-11-13 Liming Wang , Eduardo Sontag

Biological molecular machines are bifunctional enzymes that catalyze two processes: one donating free energy and the other accepting it. Recent studies show that most protein enzymes have rich stochastic dynamics of transitions between the…

Biological Physics · Physics 2023-02-02 Michal Kurzynski , Przemyslaw Chelminiak

Concurrent presence of inter-cell and intra-cell interferences constitutes a major impediment to reliable downlink transmission in multi-cell multiuser networks. Harnessing such interferences largely hinges on two levels of information…

Information Theory · Computer Science 2016-08-24 Ali Tajer , Xiaodong Wang

The mitogen-activated protein kinase (MAPK) signaling cascade, an evolutionarily conserved motif present in all eukaryotic cells, is involved in coordinating critical cell-fate decisions, regulating protein synthesis, and mediating learning…

Subcellular Processes · Quantitative Biology 2024-06-11 Tanmay Mitra , Shakti N. Menon , Sitabhra Sinha

The ubiquity of information transmission via molecular communication between cells is comprehensively documented on Earth; this phenomenon might even have played a vital role in the origin(s) and early evolution of life. Motivated by these…

Earth and Planetary Astrophysics · Physics 2024-01-26 Manasvi Lingam

In this paper, we introduce a mathematical approach for system-level analysis and optimization of densely deployed multiple-antenna cellular networks, where low-energy devices are capable of decoding information data and harvesting power…

Information Theory · Computer Science 2016-08-30 Lam Thanh Tu , Marco Di Renzo , Justin P. Coon

Due to the redundant nature of DNA synthesis and sequencing technologies, a basic model for a DNA storage system is a multi-draw "shuffling-sampling" channel. In this model, a random number of noisy copies of each sequence is observed at…

Information Theory · Computer Science 2021-12-06 Kel Levick , Reinhard Heckel , Ilan Shomorony

Where do entangled multiple-qubit systems store information? For information injected into a qubit, this question is nontrivial and interesting since the entanglement delocalizes the information. So far, a common picture is that of a qubit…

Quantum Physics · Physics 2019-04-11 Koji Yamaguchi , Naoki Watamura , Masahiro Hotta

Information theory has explained the organization of many biological phenomena, from the physiology of sensory receptive fields to the variability of certain DNA sequence ensembles. Some scholars have proposed that information should…

Other Quantitative Biology · Quantitative Biology 2010-10-25 Edward K. Agarwala , Hillel J. Chiel , Peter J. Thomas

Information must take up space, must weigh, and its flux must be limited. Quantum limits on communication and information storage leading to these conclusions are here described. Quantum channel capacity theory is reviewed for both steady…

Quantum Physics · Physics 2015-06-26 Jacob D. Bekenstein , Marcelo Schiffer

The methylation of DNA regulates gene expression. On cell division the methylation state of the DNA is typically inherited from parent to daughter cells. While the chemical bond between the methyl group and the DNA is very strong, changes…

Populations and Evolution · Quantitative Biology 2012-10-05 Sean P Stromberg

We study the amount of reliable information that can be stored in a DNA-based storage system composed of short DNA molecules. In this regime, Shomorony and Heckel (2022) put forward a conjecture on the scaling of the number of information…

Information Theory · Computer Science 2025-11-19 Ran Tamir , Nir Weinberger , Albert Guillén i Fàbregas

Storage lifetime and capacity are two important factors to characterize the performance of a quantum memory. Here we report the stable trapping of above 200 ions in a cryogenic setup, and demonstrate the combination of the multi-qubit…

Quantum Physics · Physics 2023-01-04 R. Yao , W. -Q. Lian , Y. -K. Wu , G. -X. Wang , B. -W. Li , Q. -X. Mei , B. -X. Qi , L. Yao , Z. -C. Zhou , L. He , L. -M. Duan

The utilization of multiple phosphorylation sites in regulating a biological response is ubiquitous in cell signaling. If each site contributes an additional, equivalent binding site, then one consequence of an increase in the number of…

Subcellular Processes · Quantitative Biology 2009-11-13 Jason W. Locasale

Cells are constantly exposed to fluctuating environmental conditions. External signals are sensed, processed and integrated by cellular signal transduction networks, which translate input signals into specific cellular responses by means of…

Molecular Networks · Quantitative Biology 2012-05-29 Pau Rué , Núria Domedel-Puig , Jordi Garcia-Ojalvo , Antonio J. Pons

DNA-based storage is an emerging storage technology that provides high information density and long duration. Due to the physical constraints in the reading and writing processes, error correction in DNA storage poses several interesting…

Information Theory · Computer Science 2023-10-04 Jin Sima , Netanel Raviv , Moshe Schwartz , Jehoshua Bruck

The length distribution of proteins measured in amino acids follows the CoHSI (Conservation of Hartley-Shannon Information) probability distribution. In previous papers we have verified various predictions of this using the Uniprot database…

Other Quantitative Biology · Quantitative Biology 2018-10-23 Les Hatton , Gregory Warr

It has been shown that sets of oscillators in a modular network can exhibit a rich variety of metastable chimera states, in which synchronisation and desynchronisation coexist. Independently, under the guise of integrated information…

Neurons and Cognition · Quantitative Biology 2016-06-28 Pedro A. M. Mediano , Juan Carlos Farah , Murray Shanahan

Quantum systems are inherently dissipation-less, making them excellent candidates even for classical information processing. We propose to use an array of large-spin quantum magnets for realizing a device which has two modes of operation:…

Quantum Physics · Physics 2015-10-29 Ning Jia , Leonardo Banchi , Abolfazl Bayat , Guangjiong Dong , Sougato Bose

Random-access quantum memories may offer computational advantages for quantum computers and networks. In this paper, we advance arrays of solid-state quantum memories towards their usage as random-access quantum memory. We perform quantum…

Quantum Physics · Physics 2025-09-16 Markus Teller , Susana Plascencia , Samuele Grandi , Hugues de Riedmatten