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A commonly accepted feature of an excitable medium is that a local excitation leads to a propagation of circular or spiral excitation wave-fronts. This is indeed the case in fully excitable medium. However, with a decrease of an…

Emerging Technologies · Computer Science 2019-04-16 Andrew Adamatzky

The Fitzhugh-Nagumo equations have been used as a caricature of the Hodgkin-Huxley equations of neuron firing to better understand the essential dynamics of the interaction of the membrane potential and the restoring force and to capture,…

Neurons and Cognition · Quantitative Biology 2007-05-23 F. Berezovskaya , E. Camacho , S. Wirkus , G. Karev

Periodic pulse train stimulation is generically used to study the function of the nervous system and to counteract disease-related neuronal activity, e.g., collective periodic neuronal oscillations. The efficient control of neuronal…

Adaptation and Self-Organizing Systems · Physics 2020-08-05 Kestutis Pyragas , Augustinas P. Fedaravičius , Tatjana Pyragienė

This work deals with the position control of selected patterns in reaction-diffusion systems. Exemplarily, the Schl\"{o}gl and FitzHugh-Nagumo model are discussed using three different approaches. First, an analytical solution is proposed.…

Pattern Formation and Solitons · Physics 2016-04-25 Christopher Ryll , Jakob Löber , Steffen Martens , Harald Engel , Fredi Tröltzsch

We examine traveling-wave solutions on a regular ring network with one additional long-range link that spans a distance d. The nodes obey the FitzHugh-Nagumo kinetics in the excitable regime. The additional shortcut induces a plethora of…

Adaptation and Self-Organizing Systems · Physics 2015-06-23 Thomas Isele , Benedikt Hartung , Philipp Hövel , Eckehard Schöll

This article communicates results on regular depolarization cascades in periodically-kicked feedforward chains of excitable two-dimensional FitzHugh-Nagumo systems driven by sufficiently strong excitatory forcing at the front node. The…

Dynamical Systems · Mathematics 2021-12-21 B. Ambrosio , S. M. Mintchev

We study a system of differential equation simulating transport phenomena in active structured media. The model is a generalization of the McKean s modification of the celebrated FitzHugh--Nagumo system, describing the nerve impulse…

Mathematical Physics · Physics 2015-06-11 Wojciech Likus , Vsevolod A. Vladimirov

Understanding how external stimuli propagate in neural systems is an important challenge in the fields of neuroscience and nonlinear dynamics. Despite extensive studies over several decades, this problem remains poorly understood. In this…

Neurons and Cognition · Quantitative Biology 2025-03-13 L. Messee Goulefack , C. Masoller , R. Yamapi , C. Anteneodo

Transient wave forms in neural networks with diffusive and nonlocal coupling have attracted particular interest because they may mediate recruitment of healthy cortical tissue into a pathological state during migraine. To investigate this…

Pattern Formation and Solitons · Physics 2007-08-01 Markus A. Dahlem , Felix M. Schneider , Anastasiya Panchuk , Gerald Hiller , Eckehard Schoell

We apply the framework of optimal nonlinear control to steer the dynamics of a whole-brain network of FitzHugh-Nagumo oscillators. Its nodes correspond to the cortical areas of an atlas-based segmentation of the human cerebral cortex, and…

Neurons and Cognition · Quantitative Biology 2021-09-08 Teresa Chouzouris , Nicolas Roth , Caglar Cakan , Klaus Obermayer

Brain operates at remarkably low signal power. It has been noted that noise may play a constructive role in neural networks and facilitate the subthreshold signaling. The process of spiking pattern excitation at the characteristic neuronal…

Neurons and Cognition · Quantitative Biology 2024-08-12 Mariia Sorokina

The FitzHugh-Nagumo equation, originally conceived in neuroscience during the 1960s, became a key model providing a simplified view of excitable neuron cell behavior. Its applicability, however, extends beyond neuroscience into fields like…

Pattern Formation and Solitons · Physics 2025-01-08 Daniel Cebrián-Lacasa , Pedro Parra-Rivas , Daniel Ruiz-Reynés , Lendert Gelens

We investigate smooth and sparse optimal control problems for convective FitzHugh-Nagumo equation with travelling wave solutions in moving excitable media. The cost function includes distributed space-time and terminal observations or…

Optimization and Control · Mathematics 2017-04-25 Murat Uzunca , Tuğba Küçükseyhan , Hamdullah Yücel , Bülent Karasözen

The use of high-frequency currents in neurostimulation has received increased attention in recent years due to its varied effects on tissues and cells. Nonlinear differential equations are commonly used as models for Neurons, and averaging…

Analysis of PDEs · Mathematics 2025-12-29 Eduardo Cerpa , Matías Courdurier , Esteban Hernández , Leonel E. Medina , Esteban Paduro

Excitable media are a generic class of models used to simulate a wide variety of natural systems including cardiac tissue. Propagation of excitation waves in this medium results in the formation of characteristic patterns such as rotating…

Chaotic Dynamics · Physics 2011-11-10 Sitabhra Sinha , S. Sridhar

We study a system of nonlinear differential equations simulating transport phenomena in active media. The model we are interested in is a generalization of the celebrated FitzHugh-Nagumo system, describing the nerve impulse propagation in…

Pattern Formation and Solitons · Physics 2019-05-07 Aleksandra Gawlik , Vsevolod Vladimirov , Sergii Skurativskyi

Neuronal excitability is the phenomena that describes action potential generation due to a stimulus input. Commonly, neuronal excitability is divided into two classes: Type I and Type II, both having different properties that affect…

Neurons and Cognition · Quantitative Biology 2020-11-03 Jantine A. C. Broek , Guillaume Drion

In this paper, we study an excitable, biophysical system that supports wave propagation of nerve impulses. We consider a slow-fast, FitzHugh-Rinzel neuron model where only the membrane voltage interacts diffusively, giving rise to the…

Chaotic Dynamics · Physics 2021-11-03 A. Mondal , A. Mondal , S. Kumar Sharma , R. Kumar Upadhyay , C. G. Antonopoulos

We study invasion fronts in the FitzHugh--Nagumo equation in the oscillatory regime using singular perturbation techniques. Phenomenologically, localized perturbations of the unstable steady-state grow and spread, creating temporal…

Pattern Formation and Solitons · Physics 2018-12-05 Paul Carter , Arnd Scheel

We consider a nonlinear reaction diffusion system of parabolic type known as the monodomain equations, which model the interaction of the electric current in a cell. Together with the FitzHugh-Nagumo model for the nonlinearity they…

Optimization and Control · Mathematics 2021-01-27 Thomas Berger , Tobias Breiten , Marc Puche , Timo Reis
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