Other Quantitative Biology
In this work we propose a mathematical model, based in a modified version of the Lotka-Volterra prey-predator equations, to predict the increasing in CO2 atmospheric concentration. We consider how the photosynthesis rate has changed with…
This work presents a mathematical model that establishes an interesting connection between nucleotide frequencies in human single-stranded DNA and the famous Fibonacci's numbers. The model relies on two assumptions. First, Chargaff's second…
We propose a class of microstructurally informed models for the linear elastic mechanical behavior of cross-linked polymer networks such as the actin cytoskeleton. Salient features of the models include the possibility to represent…
The nematode Caenorhabditis elegans responds to an impressive range of chemical, mechanical and thermal stimuli and is extensively used to investigate the molecular mechanisms that mediate chemosensation, mechanotransduction and…
This paper investigates the effect of drug treatment on the standard within-host HIV model, assuming that therapy occurs periodically. It is shown that eradication is possible under these periodic regimes, and we quantitatively characterize…
In the study of the basic properties observed in the immune system and, in a broader view, in biological systems, several concepts have already been mathematically formulated or treated in an analytical perspective, such as degeneracy,…
Background: The global spread of the severe acute respiratory syndrome (SARS) epidemic has clearly shown the importance of considering the long-range transportation networks in the understanding of emerging diseases outbreaks. The…
This paper proposes a systemic perspective for some aspects of both phylogenesis and ontogenesis, in the light of the notion of biological organization as negative entropy, following some hints by Schroedinger. To this purpose, we introduce…
In this paper I show that, for a class of reaction networks, the discrete stochastic nature of the reacting species and reactions results in qualitative and quantitative differences between the mean of exact stochastic simulations and the…
Apart from being the gateway for all access to the eukaryotic genome, chromatin has in recent years been identified as carrying an epigenetic code regulating transcriptional activity. The detailed knowledge of this code contrasts the…
Robust and efficient optimization methods for variance component estimation using Restricted Maximum Likelihood (REML) models for genetic mapping of quantitative traits are considered. We show that the standard Newton-AI scheme may fail…
Yet in spite of advances in hospital treatment, hospitals continue to be a breeding ground for several airborne diseases and for diseases that are transmitted through close contacts like SARS, methicillin-resistant Staphylococcus aureus…
Effect of terahertz radiation (3.6 THz, 81.5 mkm,15 mV) on some behavioral patterns of intact mice has been investigated. In home cage mice demonstrated avoidance of laser ray and enhanced replacement activity in free behavior. Animals…
A simplified model of the bird skeleton along with elongation parameters for the flight feathers is used to explore the diversity of bird shapes. Varying a small number of parameters simulates a wide range of observed bird silhouettes. The…
Theoretical analysis of own and literature investigations of sexual motivation with the use of the partition test [Kudryavtseva, 1987, 1994] in male mice was carried out. It has been shown that appearance of a receptive female in the…
Possible variant of people's infection by bird flu pathogenic culture in passing of everyday infection is presented in the work: through the contact of open parts of the skin with infected surfaces of the vehicle, that is the sequent of the…
A cell membrane can be simply regarded as composite material consisting of lipid bilayer, membrane cytoskeleton beneath lipid bilayer, and proteins embedded in lipid bilayer and linked with membrane cytoskeleton if one only concerns its…
Comment on "Classification Scheme for Phenomenological Universalities in Growth Problems in Physics and Other Sciences" by P. Castorina, P. P. Delsanto and C. Guiot, Phys. Rev. Lett. {\bf 96}, 188701 (2006) is presented. It has been proved…
Comment on the Waliszewski's article "A principle of fractal-sto-chastic dualism and Gompertzian dynamics of growth and self-organization" (BioSystems 82 (2005)61-73) is presented. It has been proved that the main idea of this work that…
A novel approach to protein multiple sequence alignment is discussed: substantially this method counterparts with substitution matrix based methods (like Blosum or PAM based methods), and implies a more deterministic approach to…