Other Quantitative Biology
Biological measurements are commonly assumed to approximate Gaussian distributions, and normality is routinely assessed as a prerequisite for statistical analysis. However, whether the degree of Gaussianity itself contains biological…
Disturbance regimes and nutrient inputs are changing worldwide, with consequences for the structure and functioning of plant communities. Classical life-history theory predicts that disturbance should shift communities from long-lived…
We propose a mathematical framework for organizational psychology based on a Maximum Entropy model of a group's personalities. The Maximum Entropy model is then decimated to a single ``collective personality''. If the original personality…
Seeds are fundamental to agricultural productivity but also act as potential vectors for pathogens, leading to substantial losses at seedling emergence. This study focuses on one major arable crop (i.e., Wheat) which is subject to…
Sociability toward humans is a key adaptive trait in free-ranging dogs, enabling them to access resources while navigating risks associated with human interactions. In this study, we investigated whether operant conditioning shapes…
Purpose: Repeated heading of soccer balls has raised concerns of potential long-term neurological effects. Consequently, numerous studies have estimated head kinematics and brain deformation due to soccer headers across different cohorts…
While AI holds the potential to revolutionize space life sciences, realizing this promise is contingent upon the systematic restructuring of heterogeneous spaceflight biological data into machine-actionable, AI-ready forms. Even though open…
Large language model (LLM) serving creates environmental impacts beyond carbon and water, including ecosystem damage through biodiversity-related pathways. We present BIRDS, a framework for Biodiversity Impact of Request-Driven LLM Serving.…
Simulation of post-prandial pharmacokinetics, such as muscle protein synthesis (MPS) through mTORC1 and insulin-induced glucose uptake, is often challenging due to the computational intensity of the multi-compartmental approach. In this…
Biological systems exhibit marked molecular asymmetry, with proteins based predominantly on L-amino acids and nucleic acids and carbohydrates largely composed of D-sugars. Explanations for homochirality include asymmetric photochemistry,…
We present an investigation of the applicability of topological data analysis (TDA) to the study of high-resolution confocal microscopy images of fibrin network structures from patients with oesophageal cancer undergoing intended curative…
One of the main causes of death around the globe is malaria. Researchers have sought to develop predictive models for malaria outbreaks based on meteorological data, climate data and the breeding cycle of Plasmodium, the causative agent of…
Ligand receptor interactions are commonly assessed through equilibrium occupancy and pharmacodynamic measures that describe binding and saturation by means of bounded response curves. Thermodynamic approaches relate binding affinity to…
Clinical interpretation often assumes that observable performance provides sufficient information about the organization of an adaptive system. However, similar observable performance may correspond to distinct latent organizations. This…
One of the great phytogeography zones of semi-arid lands in the world is the Kurdistan region of Iraq which hosts many important fruit species due to its geographical location and ecology. Mountain Hawthorn (Crataegus spp.) is a vital wild…
Importance: The 2026 multisociety dyslipidemia guideline recommended the PREVENT equations in place of the PCE equations, introduced 30-year risk assessment as a new treatment pathway, and lowered risk-based treatment thresholds. The net…
A central challenge in the origin of life is understanding how catalytic peptide-like polymers and information-bearing nucleic acid-like polymers emerged as an interde-pendent system. This study constructs a primordial cognitive model…
Diabetic foot ulcers (DFUs) are a severe complication of diabetes associated with significant morbidity, amputation risk, and healthcare burden. Developing effective continuous monitoring frameworks requires first establishing reliable…
Managing patients with respiratory failure increasingly involves noninvasive respiratory support (NIRS) strategies to support respiration, often preventing the need for invasive mechanical ventilation. However, despite the rapidly expanding…
Understanding the development of adolescent behavioral and mental health outcomes requires integrating genetic predisposition, environmental exposures, and neurobiological processes over time. Here, we present a unified quantitative…