English

Stochastic synchronization of genetic oscillators induced by miRNA

Molecular Networks 2014-09-09 v1

Abstract

We study two important roles of miRNA as stress inducer and synchronizing agent in regulating diffusively coupled genetic oscillators within stochastic formalism and competition between them. We identify optimal value of coupling constant at which the rate of synchronization is strongest, below this value sychronizing activity dominates stress activity, and above it stress activity destroys synchronizing pattern. The concentration of miRNA maintained in individual oscillator modulates the synchronization activity achieved by diffusing miRNA.

Keywords

Cite

@article{arxiv.1409.2331,
  title  = {Stochastic synchronization of genetic oscillators induced by miRNA},
  author = {Saurabh Kumar Sharma and Shakti Nath Singh and Md. Jahoor Alam and R. K. Brojen Singh},
  journal= {arXiv preprint arXiv:1409.2331},
  year   = {2014}
}