Ionic currents accompanying DNA translocation strongly depend on molarity of the electrolyte solution and the shape and surface charge of the nanopore. By means of the Poisson-Nernst-Planck equations it is shown how conductance is modulated by the presence of the DNA intruder and as a result of competing electrostatic and confinement factors. The theoretical results reproduce quantitatively the experimental ones and are summarized in a conductance diagram that allows distinguishing the region of reduced conductivity from the region of enhanced conductivity as a function of molarity and the pore dimension.
@article{arxiv.1507.04160,
title = {Steric modulation of ionic currents in DNA translocation through nanopores},
author = {Valerio Mazzone and Simone Melchionna and Umberto Marini Bettolo Marconi},
journal= {arXiv preprint arXiv:1507.04160},
year = {2015}
}