English

Random field theory-based p-values: A review of the SPM implementation

Quantitative Methods 2021-08-10 v3

Abstract

P-values and null-hypothesis significance testing are popular data-analytical tools in functional neuroimaging. Sparked by the analysis of resting-state fMRI data, there has been a resurgence of interest in the validity of some of the p-values evaluated with the widely used software SPM in recent years. The default parametric p-values reported in SPM are based on the application of results from random field theory to statistical parametric maps, a framework commonly referred to as RFT. While RFT was established two decades ago and has since been applied in a plethora of fMRI studies, there does not exist a unified documentation of the mathematical and computational underpinnings of RFT as implemented in current versions of SPM. Here, we provide such a documentation with the aim of contributing to contemporary efforts towards higher levels of computational transparency in functional neuroimaging.

Cite

@article{arxiv.1808.04075,
  title  = {Random field theory-based p-values: A review of the SPM implementation},
  author = {Dirk Ostwald and Sebastian Schneider and Rasmus Bruckner and Lilla Horvath},
  journal= {arXiv preprint arXiv:1808.04075},
  year   = {2021}
}
R2 v1 2026-06-23T03:31:41.113Z