Oscillation in microRNA Feedback Loop
Molecular Networks
2013-12-17 v3 Pattern Formation and Solitons
Abstract
The dynamic behaviors of microRNA and mRNA under external stress are studied with biological experiments and mathematics models. In this study, we developed a mathematic model to describe the biological phenomenon and for the first time reported that, as responses to external stress, the expression levels of microRNA and mRNA sustained oscillation. And the period of the oscillation is much shorter than several reported transcriptional regulation negative feedback loop.
Keywords
Cite
@article{arxiv.1304.5836,
title = {Oscillation in microRNA Feedback Loop},
author = {Bin Ao and Sheng Zhang and Caiyong Ye and Lei Chang and Guangming Zhou and Lei Yang},
journal= {arXiv preprint arXiv:1304.5836},
year = {2013}
}
Comments
There were some mistakes in the analysis in this paper's first version submitted on 22 Apr 2013. We corrected them in the second version submitted on 23 Sep 2013. So please delete the "v1" version of this paper, Thank you!