English

Molecular recognition in a lattice model: An enumeration study

Biological Physics 2009-11-11 v2 Chemical Physics

Abstract

We investigate the mechanisms underlying selective molecular recognition of single heteropolymers at chemically structured planar surfaces. To this end, we study systems with two-letter (HP) lattice heteropolymers by exact enumeration techniques. Selectivity for a particular surface is defined by an adsorption energy criterium. We analyze the distributions of selective sequences and the role of mutations. A particularly important factor for molecular recognition is the small-scale structure on the polymers.

Keywords

Cite

@article{arxiv.physics/0501016,
  title  = {Molecular recognition in a lattice model: An enumeration study},
  author = {Thorsten Bogner and Andreas Degenhard and Friederike Schmid},
  journal= {arXiv preprint arXiv:physics/0501016},
  year   = {2009}
}

Comments

revised version with additional plots