Master equation approach to protein folding
Statistical Mechanics
2009-09-25 v3 Biological Physics
q-bio
Abstract
The dynamics of two 12-monomer heteropolymers on the square lattice is studied exactly within the master equation approach. The time evolution of the occupancy of the native state is determined. At low temperatures, the median folding time follows the Arrhenius law and is governed by the longest relaxation time. For good folders, significant kinetic traps appear in the folding funnel whereas for bad folders, the traps also occur in non-native energy valleys.
Cite
@article{arxiv.cond-mat/9806313,
title = {Master equation approach to protein folding},
author = {Marek Cieplak and Malte Henkel and Jayanth R. Banavar},
journal= {arXiv preprint arXiv:cond-mat/9806313},
year = {2009}
}
Comments
Latex, 6 pages, including 7 postscript figures. Typos corrected