Master equation approach to protein folding and kinetic traps
Statistical Mechanics
2009-10-31 v2 High Energy Physics - Lattice
Biological Physics
q-bio
Abstract
The master equation for 12-monomer lattice heteropolymers is solved numerically and the time evolution of the occupancy of the native state is determined. At low temperatures, the median folding time follows the Arrhenius law and is governed by the longest relaxation time. For good folders, significant kinetic traps appear in the folding funnel whereas for bad folders, the traps also occur in non-native energy valleys.
Keywords
Cite
@article{arxiv.cond-mat/9803019,
title = {Master equation approach to protein folding and kinetic traps},
author = {Marek Cieplak and Malte Henkel and Jan Karbowski and Jayanth R. Banavar},
journal= {arXiv preprint arXiv:cond-mat/9803019},
year = {2009}
}
Comments
4 pages, Latex, 3 figures as uuencoded ps files