Four-states phase diagram of proteins
Statistical Mechanics
2009-11-11 v1
Abstract
A four states phase diagram for protein folding as a function of temperature and solvent quality is derived from an improved 2-d lattice model taking into account the temperature dependence of the hydrophobic effect. The phase diagram exhibits native, globule and two coil-type regions. In agreement with experiment, the model reproduces the phase transitions indicative of both warm and cold denaturations. Finally, it predicts transitions between the two coil states and a critical point.
Cite
@article{arxiv.cond-mat/0509138,
title = {Four-states phase diagram of proteins},
author = {Olivier Collet},
journal= {arXiv preprint arXiv:cond-mat/0509138},
year = {2009}
}
Comments
7 pages, 5 figures. Accepted for publication in Europhysics Letters