Equilibrium correlations in a model for multidimensional epistasis
Biological Physics
2007-05-23 v1 q-bio
Abstract
We investigate a statistical model for multidimensional epistasis. The genotype is devided into subsequences, and within each subsequence mutations which occur in a prescribed order are beneficial. The bit-string model used to represent the genotype, may be cast in the form of a ferromagnetic Ising model with a staggered field. We obtain the actual correlations between mutations at different sites, within an equilibrium population at a given "tolerance," which we define to be the temperature of the statistical ensemble.
Cite
@article{arxiv.physics/0208100,
title = {Equilibrium correlations in a model for multidimensional epistasis},
author = {G. Soyler and A. Erzan},
journal= {arXiv preprint arXiv:physics/0208100},
year = {2007}
}
Comments
3 pages, figures available seperately as .eps files