English

Hamiltonian model for multidimensional epistasis

Biological Physics 2015-06-26 v2 q-bio

Abstract

We propose and solve a Hamiltonian model for multidimensional epistastatic interactions between beneficial mutations. The model is able to give rise either to a phase transition between two equilibrium states, without any coexistence, or exhibits a state where hybrid species can coexist, with gradual passage from one wild type to another. The transition takes place as a function of the "tolerance" of the environment, which we define as the amount of noise in the system.

Keywords

Cite

@article{arxiv.physics/0207079,
  title  = {Hamiltonian model for multidimensional epistasis},
  author = {Seher Ozcelik and Ayse Erzan},
  journal= {arXiv preprint arXiv:physics/0207079},
  year   = {2015}
}

Comments

3 pages, 2 figures (in seperate files) spelling corrected and a reference added