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A Solid-State System for High Temporal Resolution Fluorescence Lifetime Measurements

Soft Condensed Matter 2008-03-24 v1
Authors: M. Gersbach , D. L. Boiko , C. Niclass , C. Petersen , E. Charbon
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Abstract

A system for time-correlated single photon counting applications based on CMOS single photon avalanche diodes is presented. An instrument response function of 79 ps allows a fluorescence decay of high-affinity Ca2+ indicator Oregon Green BAPTA-1 to be analyzed with unprecedented temporal resolution in the two-photon excitation regime. A triple exponential decay model is shown to best fit the fluorescence dynamics of OGB-1.

Cite

@article{arxiv.0803.3086,
  title  = {A Solid-State System for High Temporal Resolution Fluorescence Lifetime Measurements},
  author = {M. Gersbach and D. L. Boiko and C. Niclass and C. Petersen and E. Charbon},
  journal= {arXiv preprint arXiv:0803.3086},
  year   = {2008}
}

Comments

9 pages, 4 figures

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