A diploid population model for copy number variation of genetic elements
Probability
2023-02-28 v3 Populations and Evolution
Abstract
We study the following model for a diploid population of constant size : Every individual carries a random number of (genetic) elements. Upon a reproduction event each of the two parents passes each element independently with probability on to the offspring. We study the process , where is the frequency of individuals at time that carry elements, and prove convergence (in some weak sense) of jointly with its empirical first moment to the ``slow-fast'' system , where and evolves according to a critical Feller branching process. We discuss heuristics explaining this finding and some extensions and limitations.
Keywords
Cite
@article{arxiv.2204.11140,
title = {A diploid population model for copy number variation of genetic elements},
author = {Peter Pfaffelhuber and Anton Wakolbinger},
journal= {arXiv preprint arXiv:2204.11140},
year = {2023}
}
Comments
15 pages, 1 figure