What do we know about DNA mechanics so far?
Biological Physics
2020-07-01 v1 Soft Condensed Matter
Statistical Mechanics
Chemical Physics
Abstract
The DNA molecule, apart from carrying the genetic information, plays a crucial role in a variety of biological processes and find applications in drug design, nanotechnology and nanoelectronics. The molecule undergoes significant structural transitions under the influence of forces due to physiological and non-physiological environments. Here, we summarize the insights gained from simulations and single-molecule experiments on the structural transitions and mechanics of DNA under force, as well as its elastic properties, in various environmental conditions, and discuss appealing future directions.
Keywords
Cite
@article{arxiv.2006.00822,
title = {What do we know about DNA mechanics so far?},
author = {Abhishek Aggarwal and Supriyo Naskar and Anil Kumar Sahoo and Santosh Mogurampelly and Ashok Garai and Prabal K. Maiti},
journal= {arXiv preprint arXiv:2006.00822},
year = {2020}
}
Comments
Review Article, Accepted for publication in Current Opinion in Structural Biology