English

Stochastic mRNA production by a three-state gene

Dynamical Systems 2022-05-20 v1 Quantitative Methods

Abstract

We consider a model of mRNA production governed by the dynamics of a gene that exists in three possible states -- inactive, poised and active. The transitions between the adjacent states are controlled by stochastic processes characterized by corresponding on/off rates. mRNA is produced only when the gene is in active state and we also consider mRNA denaturation leading to its death.

Cite

@article{arxiv.2205.09271,
  title  = {Stochastic mRNA production by a three-state gene},
  author = {Boris Rubinstein and Jay Unruh and Julia Zeitlinger},
  journal= {arXiv preprint arXiv:2205.09271},
  year   = {2022}
}

Comments

7 pages, 3 figures

R2 v1 2026-06-24T11:21:45.227Z