Quasispecies evolution in general mean-field landscapes
Disordered Systems and Neural Networks
2009-11-07 v2 Adaptation and Self-Organizing Systems
Populations and Evolution
Abstract
I consider a class of fitness landscapes, in which the fitness is a function of a finite number of phenotypic "traits", which are themselves linear functions of the genotype. I show that the stationary trait distribution in such a landscape can be explicitly evaluated in a suitably defined "thermodynamic limit", which is a combination of infinite-genome and strong selection limits. These considerations can be applied in particular to identify relevant features of the evolution of promoter binding sites, in spite of the shortness of the corresponding sequences.
Cite
@article{arxiv.cond-mat/0105379,
title = {Quasispecies evolution in general mean-field landscapes},
author = {Luca Peliti},
journal= {arXiv preprint arXiv:cond-mat/0105379},
year = {2009}
}
Comments
6 pages, 2 figures, Europhysics Letters style (included) Finite-size scaling analysis sketched. To appear in Europhysics Letters