Quantum noise limited nanoparticle detection with exposed-core fiber
Quantum Physics
2019-07-24 v1 Applied Physics
Optics
Abstract
Label-free biosensors are important tools for clinical diagnostics and for studying biology at the single molecule level. The development of optical label-free sensors has allowed extreme sensitivity, but can expose the biological sample to photodamage. Moreover, the fragility and complexity of these sensors can be prohibitive to applications. To overcome these problems, we develop a quantum noise limited exposed-core fiber sensor providing robust platform for label-free biosensing with a natural path toward microfluidic integration. We demonstrate the detection of single nanoparticles down to 25 nm in radius with optical intensities beneath known biophysical damage thresholds.
Cite
@article{arxiv.1904.12020,
title = {Quantum noise limited nanoparticle detection with exposed-core fiber},
author = {Nicolas P. Mauranyapin and Lars S. Madsen and Larnii Booth and Lu Peng and Stephen C. Warren-Smith and Erik Schartner and Heike Ebendorff-Heidepriem and Warwick P. Bowen},
journal= {arXiv preprint arXiv:1904.12020},
year = {2019}
}
Comments
11 pages, 6 figures