Singular-phase nanooptics: towards label-free single molecule detection
Abstract
Non-trivial topology of phase is crucial for many important physics phenomena such as, for example, the Aharonov-Bohm effect 1 and the Berry phase 2. Light phase allows one to create "twisted" photons 3, 4 , vortex knots 5, dislocations 6 which has led to an emerging field of singular optics relying on abrupt phase changes 7. Here we demonstrate the feasibility of singular visible-light nanooptics which exploits the benefits of both plasmonic field enhancement and non-trivial topology of light phase. We show that properly designed plasmonic nanomaterials exhibit topologically protected singular phase behaviour which can be employed to radically improve sensitivity of detectors based on plasmon resonances. By using reversible hydrogenation of graphene 8 and a streptavidin-biotin test 9, we demonstrate areal mass sensitivity at a level of femto-grams per mm2 and detection of individual biomolecules, respectively. Our proof-of-concept results offer a way towards simple and scalable single-molecular label-free biosensing technologies.
Cite
@article{arxiv.1404.4228,
title = {Singular-phase nanooptics: towards label-free single molecule detection},
author = {V. G. Kravets and F. Schedin and R. Jalil and L. Britnell and R. V. Gorbachev and D. Ansell and B. Thackray and K. S. Novoselov and A. K. Geim and A. V. Kabashin and A. N. Grigorenko},
journal= {arXiv preprint arXiv:1404.4228},
year = {2014}
}
Comments
19 pages, 4 figures