Protein folding in a force-clamp
Biomolecules
2009-11-13 v1
Abstract
Kinetics of folding of a protein held in a force-clamp are compared to an unconstrained folding. The comparison is made within a simple topology-based dynamical model of ubiquitin. We demonstrate that the experimentally observed variations in the end-to-end distance reflect microscopic events during folding. However, the folding scenarios in and out of the force-clamp are distinct.
Cite
@article{arxiv.q-bio/0603018,
title = {Protein folding in a force-clamp},
author = {Marek Cieplak and Piotr Szymczak},
journal= {arXiv preprint arXiv:q-bio/0603018},
year = {2009}
}
Comments
9 pages, 4 figures, Journal of Chemical Physics (in press)