Influence of Hydrodynamic Interactions on Mechanical Unfolding of Proteins
Biomolecules
2015-05-13 v1
Abstract
We incorporate hydrodynamic interactions in a structure-based model of ubiquitin and demonstrate that the hydrodynamic coupling may reduce the peak force when stretching the protein at constant speed, especially at larger speeds. Hydrodynamic interactions are also shown to facilitate unfolding at constant force and inhibit stretching by fluid flows.
Keywords
Cite
@article{arxiv.0706.1102,
title = {Influence of Hydrodynamic Interactions on Mechanical Unfolding of Proteins},
author = {P. Szymczak and Marek Cieplak},
journal= {arXiv preprint arXiv:0706.1102},
year = {2015}
}
Comments
to be published in Journal of Physics: Condensed Matter