Computer algebra in systems biology
Symbolic Computation
2008-12-19 v2 Molecular Networks
Quantitative Methods
Abstract
Systems biology focuses on the study of entire biological systems rather than on their individual components. With the emergence of high-throughput data generation technologies for molecular biology and the development of advanced mathematical modeling techniques, this field promises to provide important new insights. At the same time, with the availability of increasingly powerful computers, computer algebra has developed into a useful tool for many applications. This article illustrates the use of computer algebra in systems biology by way of a well-known gene regulatory network, the Lac Operon in the bacterium E. coli.
Cite
@article{arxiv.0712.4248,
title = {Computer algebra in systems biology},
author = {Reinhard Laubenbacher and Bernd Sturmfels},
journal= {arXiv preprint arXiv:0712.4248},
year = {2008}
}
Comments
to appear in American Mathematical Monthly