English

Modeling network dynamics: the lac operon, a case study

Molecular Networks 2007-05-23 v1 Statistical Mechanics Biological Physics Cell Behavior

Abstract

We use the lac operon in Escherichia coli as a prototype system to illustrate the current state, applicability, and limitations of modeling the dynamics of cellular networks. We integrate three different levels of description -molecular, cellular, and that of cell population- into a single model, which seems to capture many experimental aspects of the system.

Keywords

Cite

@article{arxiv.q-bio/0411036,
  title  = {Modeling network dynamics: the lac operon, a case study},
  author = {J. M. G. Vilar and C. C. Guet and S. Leibler},
  journal= {arXiv preprint arXiv:q-bio/0411036},
  year   = {2007}
}