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We show that individual vibrational modes in single-molecule junctions with asymmetric molecule-lead coupling can be selectively excited by applying an external bias voltage. Thereby, a non-statistical distribution of vibrational energy can…
Most models of neurons incorporate a capacitor to account for the marked capacitive behavior exhibited by the cell membrane. However, such capacitance is widely considered constant, thereby neglecting the possible effects of time-dependent…
Cellular decision-making based on information received from the external environment is frequently initiated by transmembrane receptors. These receptors are known to propagate such information by triggering a series of irreversible,…
This article is devoted to the mathematical modeling of migration of neuroblasts, precursor cells of neurons, along the pathway they usually follow before maturing. This pathway is determined mainly by chemotaxis and the heterogeneous…
Circadian rhythmicity lies at the center of various important physiological and behavioral processes in mammals, such as sleep, metabolism, homeostasis, mood changes and more. It has been shown that this rhythm arises from self-sustained…
Goal-directed manipulation of representations is a key element of human flexible behaviour, while consciousness is often related to several aspects of higher-order cognition and human flexibility. Currently these two phenomena are only…
Quantum tunneling, a phenomenon in which a quantum state traverses energy barriers above the energy of the state itself, has been hypothesized as an advantageous physical resource for optimization. Here we show that multiqubit tunneling…
The temporal activity of many biological systems, including neural circuits, exhibits fluctuations simultaneously varying over a large range of timescales. The mechanisms leading to this temporal heterogeneity are yet unknown. Here we show…
Unlike isolated beta-cells, which usually produce continuous spikes or fast and irregular bursts, electrically coupled beta-cells are apt to exhibit robust bursting action potentials. We consider the noise induced by thermal fluctuations as…
The observation of apparent power-laws in neuronal systems has led to the suggestion that the brain is at, or close to, a critical state and may be a self-organised critical system. Within the framework of self-organised criticality a…
We study both analytically and numerically the effect of presynaptic noise on the transmission of information in attractor neural networks. The noise occurs on a very short-time scale compared to that for the neuron dynamics and it produces…
In many-body nonlinear systems with sufficient anharmonicity, a special kind of lattice vibrations, namely, Localized Anharmonic Vibrations (LAVs) can be excited either thermally or by external triggering, in which the amplitude of atomic…
The textbook picture of nerve activity is that of a propagating voltage pulse driven by electrical currents through ion channel proteins, which are gated by changes in voltage, temperature, pressure or by drugs. All function is directly…
Seizure activity is a ubiquitous and pernicious pathophysiology that, in principle, should yield to mathematical treatments of (neuronal) ensemble dynamics - and therefore interventions on stochastic chaos. A seizure can be characterised as…
Thinking is one of the most interesting mental processes. Its complexity is sometimes simplified and its different manifestations are classified into normal and abnormal, like the delusional and disorganized thought or the creative one. The…
Neuroscience research has produced many theories and computational neural models of sensory nervous systems. Notwithstanding many different perspectives towards developing intelligent machines, artificial intelligence has ultimately been…
It is argued that human consciousness is likely to have emerged during the self-consistent evolution of the physical universe, through the gradual accumulation of biological entities' ability to tap into the intrinsic non-deterministic…
SNARE proteins zipper to form SNAREpins that power vesicle fusion with target membranes in a variety of biological processes. A single SNAREpin takes about 1 second to fuse two bilayers, yet a handful can ensure release of neurotransmitters…
The paper tackles four basic questions associated with human brain as a learning system. How can the brain learn to (1) mentally simulate different external memory aids, (2) perform, in principle, any mental computations using imaginary…
Epileptic Seizure is an abnormal neuronal exertion in the brain, affecting nearly 70 million of the world's population (Ngugi et al., 2010). So many open-source neuroimaging tools are used for metabolism checkups and analysis purposes. The…