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Changes in a cell's external or internal conditions are usually reflected in the concentrations of the relevant transcription factors. These proteins in turn modulate the expression levels of the genes under their control and sometimes need…

Molecular Networks · Quantitative Biology 2013-08-01 Gasper Tkacik , Curtis G Callan , William Bialek

We present a logical calculus for reasoning about information flow in quantum programs. In particular we introduce a dynamic logic that is capable of dealing with quantum measurements, unitary evolutions and entanglements in compound…

Quantum Physics · Physics 2021-09-15 Alexandru Baltag , Sonja Smets

Algorithmic approach is based on the assumption that any quantum evolution of many particle system can be simulated on a classical computer with the polynomial time and memory cost. Algorithms play the central role here but not the…

Quantum Physics · Physics 2007-05-23 Yuri Ozhigov

Darwinian evolution requires (i) heritable records, (ii) repeatable copying with variation, and (iii) routine irreversibility. Categorical quantum mechanics (CQM) makes precise why ``copy'' and ``delete'' are not generic quantum operations:…

Quantum Physics · Physics 2026-02-19 Partha Ghose

A model of genome evolution is proposed. Based on three assumptions the evolutionary theory of a genome is formulated. The general law on the direction of genome evolution is given. Both the deterministic classical equation and the…

Other Quantitative Biology · Quantitative Biology 2014-11-11 Liaofu Luo

A celebrated and controversial hypothesis conjectures that some biological systems --parts, aspects, or groups of them-- may extract important functional benefits from operating at the edge of instability, halfway between order and…

Statistical Mechanics · Physics 2018-08-01 Miguel A. Munoz

While evolution has inspired algorithmic methods of heuristic optimisation, little has been done in the way of using concepts of computation to advance our understanding of salient aspects of biological phenomena. We argue that under…

Computational Complexity · Computer Science 2012-06-05 Hector Zenil , James A. R. Marshall

We study the probabilities of evolution based on random mutations and natural selection. We conclude that evolution to multicellular eukaryots, or even prokaryots, is unlikely to be the result of only random mutations. Complex organisms…

Populations and Evolution · Quantitative Biology 2007-05-23 B. Hoeneisen , G. Trueba

Quantum information science is an exciting, wide, rapidly progressing, cross-disciplinary field, and that very nature makes it both attractive and hard to enter. In this primer, we first provide answers to the three essential questions that…

Quantum Physics · Physics 2020-08-14 Emina Soljanin

A rigorous thermodynamic expression is derived for the total biological information capacity per unit length of a DNA molecule. The total information includes the usual four letter coding sequence information plus that excess information…

General Physics · Physics 2012-11-27 A. Widom , J. Swain , Y. N. Srivastava , S. Sivasubramanian , V. I. Valenzi

In this paper we study the evolution of the mutation rate for simple organisms in dynamic environments. A model with multiple fitness coding loci tracking a moving fitness peak is developed and an analytical expression for the optimal…

Biological Physics · Physics 2007-05-23 Martin Nilsson , Nigel Snoad

For many-particle systems, quantum information in base n can be defined by partitioning the set of states according to the outcomes of n-ary (joint) observables. Thereby, k particles can carry k nits. With regards to the randomness of…

Quantum Physics · Physics 2015-06-26 Karl Svozil

There have been many claims that quantum mechanics plays a key role in the origin and/or operation of biological organisms, beyond merely providing the basis for the shapes and sizes of biological molecules and their chemical affinities.…

Quantum Physics · Physics 2009-11-10 P. C. W. Davies

In a certain way, this paper presents the continuation of the previous one which discussed the harmonic structure of the genetic code (Rakocevic, 2004). Several new harmonic structures presented in this paper, through specific unity and…

Other Quantitative Biology · Quantitative Biology 2007-05-23 Miloje M. Rakocevic

Since the discovery of the presence of biogenic magnetites in living organisms, there have been speculations on the role that these biomagnetites play in cellular processes. It seems that the formation of biomagnetite crystals is a…

Biological Physics · Physics 2010-12-16 Istvan Bokkon , Vahid Salari

Any process in which competing solutions replicate with errors and numbers of their copies depend on their respective fitnesses is the evolutionary optimization process. As during carcinogenesis mutated genomes replicate according to their…

Populations and Evolution · Quantitative Biology 2009-12-15 B. Brutovsky , D. Horvath

Functions of chemical composition are complex and discrete in nature making it impossible to optimize them with gradient methods. Genetic algorithms, which do not use derivative information, are used to maximize the thermal conductivity of…

Materials Science · Physics 2018-01-30 Alexander Kerr , Kieran Mullen

Quantum computing holds significant potential for applications in biology and medicine, spanning from the simulation of biomolecules to machine learning approaches for subtyping cancers on the basis of clinical features. This potential is…

We consider possible designs and experimental realiza-tions in synthesized rather than naturally occurring bio-chemical systems of a selection of basic bio-inspired information processing steps. These include feed-forward loops, which have…

Molecular Networks · Quantitative Biology 2015-02-09 Vladimir Privman , Evgeny Katz

Quantum computers can in principle solve certain problems exponentially more quickly than their classical counterparts. We have not yet reached the advent of useful quantum computation, but when we do, it will affect nearly all scientific…