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Computations on the dendritic trees of neurons have important constraints. Voltage dependent conductances in dendrites are not similar to arbitrary direct-current generation, they are the basis for dendritic nonlinearities and they do not…

Neurons and Cognition · Quantitative Biology 2021-08-12 Ilenna Simone Jones , Konrad Paul Kording

This paper represents a contribution to the study of the brain functional connectivity from the perspective of complex networks theory. More specifically, we apply graph theoretical analyses to provide evidence of the modular structure of…

Neurons and Cognition · Quantitative Biology 2016-09-06 Giampiero Bardella , Angelo Bifone , Andrea Gabrielli , Alessandro Gozzi , Tiziano Squartini

In the past two decades, functional Magnetic Resonance Imaging has been used to relate neuronal network activity to cognitive processing and behaviour. Recently this approach has been augmented by algorithms that allow us to infer causal…

Quantitative Methods · Quantitative Biology 2019-05-31 Natalia Z. Bielczyk , Sebo Uithol , Tim van Mourik , Paul Anderson , Jeffrey C. Glennon , Jan K. Buitelaar

The brain is likely the most complex organ, given the variety of functions it controls, the number of cells it comprises, and their corresponding diversity. Studying and identifying neurons, the brain's primary building blocks, is a crucial…

Machine Learning · Computer Science 2023-06-02 Ofek Ophir , Orit Shefi , Ofir Lindenbaum

The human brain has been studied at multiple scales, from neurons, circuits, areas with well defined anatomical and functional boundaries, to large-scale functional networks which mediate coherent cognition. In a recent work, we addressed…

Biological Physics · Physics 2012-05-17 Lazaros K. Gallos , Mariano Sigman , Hernan A. Makse

To understand biological intelligence we need to map neuronal networks in vertebrate brains. Mapping mesoscale neural circuitry is done using injections of tracers that label groups of neurons whose axons project to different brain regions.…

Neurons and Cognition · Quantitative Biology 2025-05-13 Samik Banerjee , Caleb Stam , Daniel J. Tward , Steven Savoia , Yusu Wang , Partha P. Mitra

The structure of the axon-dendrite connections of neurons of the brain creates a rich spatial structure in which provided various combinations of signals surrounding neurons. Structure of dendritic trees and shape of dendritic spines allow…

Artificial Intelligence · Computer Science 2014-07-25 Alexey Redozubov

We describe how hierarchical concepts can be represented in three types of layered neural networks. The aim is to support recognition of the concepts when partial information about the concepts is presented, and also when some of the…

Neural and Evolutionary Computing · Computer Science 2025-03-25 Nancy A. Lynch

Since the first experimental evidences of active conductances in dendrites, most neurons have been shown to exhibit dendritic excitability through the expression of a variety of voltage-gated ion channels. However, despite experimental and…

Neurons and Cognition · Quantitative Biology 2012-01-18 Leonardo L. Gollo , Osame Kinouchi , Mauro Copelli

Cognitive flexibility describes the human ability to switch between modes of mental function to achieve goals. Mental switching is accompanied by transient changes in brain activity, which must occur atop an anatomical architecture that…

Neurons and Cognition · Quantitative Biology 2016-11-29 John D. Medaglia , Weiyu Huang , Elisabeth A. Karuza , Sharon L. Thompson-Schill , Alejandro Ribeiro , Danielle S. Bassett

Early brain connectivity development consists of multiple stages: birth of neurons, their migration and the subsequent growth of axons and dendrites. Each stage occurs within a certain period of time depending on types of neurons and…

Neurons and Cognition · Quantitative Biology 2015-03-16 Sol Lim , Marcus Kaiser

Dynamical wiring and rewiring in neural networks are carried out by activity-dependent growth and retraction of axons and dendrites, guided by gudance molecules, released by target cells. Experience-dependent structural changes in cortical…

Neurons and Cognition · Quantitative Biology 2007-05-23 Fail M. Gafarov

A single axon can generate branches connecting with plenty synaptic targets. Process of branching is very important for making connections in central nervous system. The interstitial branching along primary axon shaft occurs during nervous…

Neurons and Cognition · Quantitative Biology 2013-04-25 Y. Suleymanov , F. Gafarov , N. Khusnutdinov

We present a study on the emergence of a variety of spatio temporal patterns among neurons that are connected in a multiplex framework, with neurons on two layers with different functional couplings. With the Hindmarsh-Rose model for the…

Adaptation and Self-Organizing Systems · Physics 2021-11-29 Umesh Kumar Verma , G. Ambika

Over the last decades, cognitive psychology has come to fair consensus about the ontological structure of human intelligence. However, it remains an open question, whether anatomical properties of the brain support the same ontology. The…

Neurons and Cognition · Quantitative Biology 2021-12-08 Daniel Kristanto , Xinyang Liu , Werner Sommer , Andrea Hildebrandt , Changsong Zhou

The brain is a paradigmatic example of a complex system as its functionality emerges as a global property of local mesoscopic and microscopic interactions. Complex network theory allows to elicit the functional architecture of the brain in…

Neurons and Cognition · Quantitative Biology 2017-01-18 Rossana Mastrandrea , Andrea Gabrielli , Fabrizio Piras , Gianfranco Spalletta , Guido Caldarelli , Tommaso Gili

Diffusion Magnetic Resonance Imaging (MRI) exploits the anisotropic diffusion of water molecules in the brain to enable the estimation of the brain's anatomical fiber tracts at a relatively high resolution. In particular, tractographic…

Computational Engineering, Finance, and Science · Computer Science 2016-09-14 Yu Jin , Joseph F. JaJa , Rong Chen , Edward H. Herskovits

We develop a Bayesian bivariate spatial model for multivariate regression analysis applicable to studies examining the influence of genetic variation on brain structure. Our model is motivated by an imaging genetics study of the Alzheimer's…

Methodology · Statistics 2020-05-26 Yin Song , Shufei Ge , Jiguo Cao , Liangliang Wang , Farouk S. Nathoo

Neurons in the brain are often finely tuned for specific task variables. Moreover, such disentangled representations are highly sought after in machine learning. Here we mathematically prove that simple biological constraints on neurons,…

Neurons and Cognition · Quantitative Biology 2023-04-04 James C. R. Whittington , Will Dorrell , Surya Ganguli , Timothy E. J. Behrens

In neuroimaging studies, the human cortex is commonly modeled as a sphere to preserve the topological structure of the cortical surface. Cortical neuroimaging measures hence can be modeled in spherical representation. In this work, we…

Computer Vision and Pattern Recognition · Computer Science 2018-12-20 Xinyang Feng , Jie Yang , Andrew F. Laine , Elsa D. Angelini