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Structure entails function and thus a structural description of the brain will help to understand its function and may provide insights into many properties of brain systems, from their robustness and recovery from damage, to their dynamics…

Neurons and Cognition · Quantitative Biology 2008-08-27 Marcus Kaiser , Robert Martin , Peter Andras , Malcolm P. Young

Intrinsic brain activity is characterized by highly structured co-activations between different regions, whose origin is still under debate. In this paper, we address the question whether it is possible to unveil how the underlying…

This paper describes how realistic neuromorphic networks can have their connectivity fully characterized in analytical fashion. By assuming that all neurons have the same shape and are regularly distributed along the two-dimensional…

Disordered Systems and Neural Networks · Physics 2007-05-23 Luciano da Fontoura Costa , Marconi Soares Barbosa

Anatomical connectivity imposes strong constraints on brain function, but there is no general agreement about principles that govern its organization. Based on extensive quantitative data we tested the power of three models to predict…

Neurons and Cognition · Quantitative Biology 2016-05-31 Sarah F. Beul , Helen Barbas , Claus C. Hilgetag

When the brain receives input from multiple sensory systems, it is faced with the question of whether it is appropriate to process the inputs in combination, as if they originated from the same event, or separately, as if they originated…

Neural and Evolutionary Computing · Computer Science 2018-03-06 Jonathan Tong , German I. Parisi , Stefan Wermter , Brigitte Röder

Large-scale neural mass models have been widely used to simulate resting-state brain activity from structural connectivity. In this work, we extend a well-established Wilson--Cowan framework by introducing a novel hemispheric-specific…

Neurons and Cognition · Quantitative Biology 2025-08-19 Ramiro Plüss , Hernán Villota , Patricio Orio

Neurons in the brain are complex machines with distinct functional compartments that interact nonlinearly. In contrast, neurons in artificial neural networks abstract away this complexity, typically down to a scalar activation function of a…

Machine Learning · Computer Science 2021-10-18 Kijung Yoon , Emin Orhan , Juhyun Kim , Xaq Pitkow

Learning and memory may rely on the ability of neuronal circuits to reorganize by dendritic spine remodeling. We have looked for geometrical parameters of cortical circuits, which maximize information storage capacity associated with this…

Biological Physics · Physics 2007-05-23 Armen Stepanyants

The macrocolumn is a key component of a neuromorphic computing system that interacts with an external environment under control of an agent. Environments are learned and stored in the macrocolumn as labeled directed graphs where edges…

Neural and Evolutionary Computing · Computer Science 2023-02-15 James E. Smith

Reconstruction of neuroanatomy is a fundamental problem in neuroscience. Stochastic expression of colors in individual cells is a promising tool, although its use in the nervous system has been limited due to various sources of variability…

Neurons and Cognition · Quantitative Biology 2017-01-24 Uygar Sümbül , Douglas Roussien , Fei Chen , Nicholas Barry , Edward S. Boyden , Dawen Cai , John P. Cunningham , Liam Paninski

Based on existing data, we wish to put forward a biological model of motor system on the neuron scale. Then we indicate its implications in statistics and learning. Specifically, neuron firing frequency and synaptic strength are probability…

Neurons and Cognition · Quantitative Biology 2014-07-28 Peilei Liu , Ting Wang

The differential diagnosis of neurodegenerative diseases, characterized by overlapping symptoms, may be challenging. Brain imaging coupled with artificial intelligence has been previously proposed for diagnostic support, but most of these…

Image and Video Processing · Electrical Eng. & Systems 2025-02-21 Pierrick Coupé , Boris Mansencal , José V. Manjón , Patrice Péran , Wassilios G. Meissner , Thomas Tourdias , Vincent Planche

We study three representations of hierarchies of partitions: dendrograms (direct representations), saliency maps, and minimum spanning trees. We provide a new bijection between saliency maps and hierarchies based on quasi-flat zones as used…

Computer Vision and Pattern Recognition · Computer Science 2015-05-28 Jean Cousty , Laurent Najman , Yukiko Kenmochi , Silvio Guimarães

The brain is composed of billions of neurons with virtually endless morphologies and ion channel compositions, resulting in unique extracellular waveforms. Nevertheless, almost all neuronal morphologies can be reduced to a simple…

Neurons and Cognition · Quantitative Biology 2026-01-12 Jérémie Sibille , Kai Lun Teh , Alexandra Tzilivaki , Dietmar Schmitz , Paula T. Kuokkanen

In the study of neurons, morphology influences function. The complexity in the structure of neurons poses a challenge in the identification and analysis of similar and dissimilar neuronal cells. Existing methodologies carry out structural…

Image and Video Processing · Electrical Eng. & Systems 2018-02-21 Tamal Batabyal , Scott T. Acton

Neural systems show a modular and typically also a hierarchical organisation across different levels and across different species. Topology relates to function, but it is also influences dynamics as earlier studies showed its effect on…

Neurons and Cognition · Quantitative Biology 2014-05-15 Marcus Kaiser

The organization of the axonal cytoskeleton is a key determinant of the normal function of an axon, which is a long thin projection away from a neuron. Under normal conditions two axonal cytoskeletal polymers microtubules and neurofilaments…

Cell Behavior · Quantitative Biology 2016-02-17 Chuan Xue , Blerta Shtylla , Anthony Brown

The second-order formula of Minkowski functionals in weakly non-Gaussian fields is compared with the numerical $N$-body simulations. Recently, weakly non-Gaussian formula of Minkowski functionals is extended to include the second-order…

Cosmology and Nongalactic Astrophysics · Physics 2020-12-03 Takahiko Matsubara , Chiaki Hikage , Satoshi Kuriki

Correlated fluctuations in the activity of neural populations reflect the network's dynamics and connectivity. The temporal and spatial dimensions of neural correlations are interdependent. However, prior theoretical work mainly analyzed…

Neurons and Cognition · Quantitative Biology 2022-07-19 Yan-Liang Shi , Roxana Zeraati , Anna Levina , Tatiana A. Engel

The genus statistics of isodensity contours has become a well-established tool in cosmology. In this Letter we place the genus in the wider framework of a complete family of morphological descriptors. These are known as the Minkowski…

Astrophysics · Physics 2009-10-30 Jens Schmalzing , Thomas Buchert
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