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A recent Cell paper [Chang and Tsao, 2017] reports an interesting discovery. For the face stimuli generated by a pre-trained active appearance model (AAM), the responses of neurons in the areas of the primate brain that are responsible for…

Computer Vision and Pattern Recognition · Computer Science 2018-05-23 Tian Han , Jiawen Wu , Ying Nian Wu

This article underlines the learning and discrimination capabilities of a model of associative memory based on artificial networks of spiking neurons. Inspired from neuropsychology and neurobiology, the model implements top-down…

Neural and Evolutionary Computing · Computer Science 2016-08-16 Anthony Mouraud , Hélène Paugam-Moisy

We consider a model of learning and evolution in games whose action sets are endowed with a partition-based similarity structure intended to capture exogenous similarities between strategies. In this model, revising agents have a higher…

Computer Science and Game Theory · Computer Science 2024-07-26 Panayotis Mertikopoulos , William H. Sandholm

Molecular circuits capable of autonomous learning could unlock novel applications in fields such as bioengineering and synthetic biology. To this end, existing chemical implementations of neural computing have mainly relied on emulating…

Machine Learning · Computer Science 2025-09-23 Rajiv Teja Nagipogu , John H. Reif

The field of artificial intelligence faces significant challenges in achieving both biological plausibility and computational efficiency, particularly in visual learning tasks. Current artificial neural networks, such as convolutional…

Machine Learning · Computer Science 2024-09-27 Jacobo Ruiz , Manas Gupta

We show that macro-molecular self-assembly can recognize and classify high-dimensional patterns in the concentrations of $N$ distinct molecular species. Similar to associative neural networks, the recognition here leverages dynamical…

Disordered Systems and Neural Networks · Physics 2017-04-26 Weishun Zhong , David J. Schwab , Arvind Murugan

Machine learning and deep learning have gained popularity and achieved immense success in Drug discovery in recent decades. Historically, machine learning and deep learning models were trained on either structural data or chemical…

Machine Learning · Statistics 2019-09-18 Huy Ngoc Pham , Trung Hoang Le

Developments in deep generative models have allowed for tractable learning of high-dimensional data distributions. While the employed learning procedures typically assume that training data is drawn i.i.d. from the distribution of interest,…

Machine Learning · Computer Science 2017-05-24 Ari Seff , Alex Beatson , Daniel Suo , Han Liu

Recent progress in artificial intelligence (AI) has been driven by insights from physics and neuroscience, particularly through the development of artificial neural networks (ANNs) capable of complex cognitive tasks such as vision and…

Neurons and Cognition · Quantitative Biology 2025-11-04 Alejandro Rodriguez-Garcia , Anindya Ghosh , Jie Mei , Srikanth Ramaswamy

Machine learning in drug discovery has been focused on virtual screening of molecular libraries using discriminative models. Generative models are an entirely different approach that learn to represent and optimize molecules in a continuous…

Quantitative Methods · Quantitative Biology 2020-11-17 Matthew Ragoza , Tomohide Masuda , David Ryan Koes

Data-driven modeling in mechanics is evolving rapidly based on recent machine learning advances, especially on artificial neural networks. As the field matures, new data and models created by different groups become available, opening…

Numerical Analysis · Mathematics 2024-03-11 Aleksandr Dekhovich , O. Taylan Turan , Jiaxiang Yi , Miguel A. Bessa

Animals behave adaptively in the environment with multiply competing goals. Understanding of the mechanisms underlying such goal-directed behavior remains a challenge for neuroscience as well for adaptive system research. To address this…

Neural and Evolutionary Computing · Computer Science 2012-04-17 Konstantin Lakhman , Mikhail Burtsev

Nonlinear systems driven by recurrent signals are known to exhibit complex dynamical responses which, in the physiological context, can have important functional consequences. One of the simplest biological systems that is exposed to such…

Subcellular Processes · Quantitative Biology 2018-07-04 Tanmay Mitra , Shakti N. Menon , Sitabhra Sinha

Introduction. Neural network models of autoassociative, distributed memory allow storage and retrieval of many items (vectors) where the number of stored items can exceed the vector dimension (the number of neurons in the network). This…

Neural and Evolutionary Computing · Computer Science 2017-09-05 V. I. Gritsenko , D. A. Rachkovskij , A. A. Frolov , R. Gayler , D. Kleyko , E. Osipov

An associative memory is a framework of content-addressable memory that stores a collection of message vectors (or a dataset) over a neural network while enabling a neurally feasible mechanism to recover any message in the dataset from its…

Machine Learning · Statistics 2016-11-30 Arya Mazumdar , Ankit Singh Rawat

The model of interaction between learning and evolutionary optimization is designed and investigated. The evolving population of modeled organisms is considered. The mechanism of the genetic assimilation of the acquired features during a…

Neural and Evolutionary Computing · Computer Science 2014-11-20 Vladimir G. Red'ko

Continual learning is the ability to sequentially learn over time by accommodating knowledge while retaining previously learned experiences. Neural networks can learn multiple tasks when trained on them jointly, but cannot maintain…

Machine Learning · Computer Science 2018-10-26 Frantzeska Lavda , Jason Ramapuram , Magda Gregorova , Alexandros Kalousis

Chemical space is routinely explored by machine learning methods to discover interesting molecules, before time-consuming experimental synthesizing is attempted. However, these methods often rely on a graph representation, ignoring 3D…

Accurate and efficient prediction of the molecular properties of drugs is one of the fundamental problems in drug research and development. Recent advancements in representation learning have been shown to greatly improve the performance of…

Biomolecules · Quantitative Biology 2022-06-17 Hui Liu , Yibiao Huang , Xuejun Liu , Lei Deng

A popular theory of perceptual processing holds that the brain learns both a generative model of the world and a paired recognition model using variational Bayesian inference. Most hypotheses of how the brain might learn these models assume…

Neurons and Cognition · Quantitative Biology 2021-06-01 Ari S. Benjamin , Konrad P. Kording
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